STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB4514Probable RNA polymerase ECF-type sigma factor; PMID: 94329558 PMID: 89024591 best DB hits: BLAST: ddbj:BAB03982.1; (AP001507) RNA polymerase ECF-type sigma factor; E=2e-07 embl:CAA09264.1; (AJ010601) ECF sigma factor [Streptomyces; E=2e-04 swissprot:Q45585; SIGW_BACSU RNA POLYMERASE SIGMA FACTOR SIGW; E=3e-04 COG: BH0263; COG1595 DNA-directed RNA polymerase specialized sigma; E=2e-08 PFAM: PF00776; Sigma-70 factor (ECF subfamily); E=3.9e-10. (238 aa)    
Predicted Functional Partners:
RB4513
PMID: 95012680 best DB hits: BLAST: pir:G75252; probable brkB protein - Deinococcus radiodurans (strain; E=3e-19 pir:I40328; serum-resistance protein brkB [imported] - Bordetella; E=2e-12 pir:A82807; BrkB protein XF0432 [imported] - Xylella fastidiosa; E=2e-09 COG: DR2609; COG1295 tRNA-processing ribonuclease BN; E=2e-20.
       0.613
sigG
Probable RNA-polymerase sigma-E factor; Best DB hits: BLAST: gb:AAD42769.1; AF121849_1 (AF121849) SigG [Synechococcus sp. PCC; E=9e-12 pir:S77368; transcription initiation factor sigma E slr1545 -; E=1e-11 pir:C82583; RNA polymerase sigma-H factor XF2239 [imported] -; E=1e-08 COG: slr1545; COG1595 DNA-directed RNA polymerase specialized sigma; E=1e-12 PFAM: PF00776; Sigma-70 factor (ECF subfamily); E=0.00072 PF00140; Sigma-70 factor; E=0.028.
  
     0.581
sigW-4
RNA polymerase sigma factor sigW; PMID: 8432708 PMID: 7961421 best DB hits: BLAST: swissprot:Q45585; SIGW_BACSU RNA POLYMERASE SIGMA FACTOR SIGW; E=1e-15 ddbj:BAB03982.1; (AP001507) RNA polymerase ECF-type sigma factor; E=5e-13 gb:AAF18265.1; U22895_1 (U22895) alternative sigma factor AlgU; E=3e-10 COG: BS_sigW; COG1595 DNA-directed RNA polymerase specialized sigma; E=1e-16 PFAM: PF00776; Sigma-70 factor (ECF subfamily); E=2.9e-11.
  
     0.564
RB4517
Probable pterin-4-alpha-carbinolamine dehydratase; PMID: 8108417 PMID: 97052967 best DB hits: BLAST: pir:C70304; 4a-hydroxytetrahydrobiopterin dehydratase (EC 4.2.1.96); E=2e-10 ddbj:BAA97373.1; (AB023044) gene_id:MWD22.5~similar to unknown; E=5e-10 swissprot:P43335; PHS_PSEAE PTERIN-4-ALPHA-CARBINOLAMINE; E=4e-09 COG: aq_049; COG2154 Pterin-4a-carbinolamine dehydratase; E=2e-11 PFAM: PF01329; Pterin 4 alpha carbinolamine dehydr; E=1.2e-18.
       0.557
RB4519
Hypothetical protein.
       0.557
rpsH
RNA polymerase sigma-H factor; PMID: 8432708 best DB hits: BLAST: pir:C82583; RNA polymerase sigma-H factor XF2239 [imported] -; E=1e-19 pir:S77368; transcription initiation factor sigma E slr1545 -; E=2e-19 gb:AAD42769.1; AF121849_1 (AF121849) SigG [Synechococcus sp. PCC; E=7e-18 COG: XF2239; COG1595 DNA-directed RNA polymerase specialized sigma; E=1e-20 PFAM: PF00776; Sigma-70 factor (ECF subfamily); E=1.5e-18 PF00140; Sigma-70 factor; E=0.55.
  
     0.532
RB12372
RNA polymerase ECF-type sigma factor; PMID: 7889934 best DB hits: BLAST: ddbj:BAB03982.1; (AP001507) RNA polymerase ECF-type sigma factor; E=4e-15 swissprot:Q45585; SIGW_BACSU RNA POLYMERASE SIGMA FACTOR SIGW; E=3e-13 swissprot:Q06198; RPSH_PSEAE RNA POLYMERASE SIGMA-H FACTOR; E=1e-11 COG: BH0263; COG1595 DNA-directed RNA polymerase specialized sigma; E=4e-16 PFAM: PF00776; Sigma-70 factor (ECF subfamily); E=5.4e-10 PF00140; Sigma-70 factor; E=0.53.
  
     0.504
RB12251
RNA polymerase ECF-type sigma factor; PMID: 7768826 best DB hits: BLAST: swissprot:P46358; RFAY_XANCP PROBABLE RNA POLYMERASE SIGMA FACTOR; E=2e-22 ddbj:BAB03982.1; (AP001507) RNA polymerase ECF-type sigma factor; E=7e-15 swissprot:Q45585; SIGW_BACSU RNA POLYMERASE SIGMA FACTOR SIGW; E=4e-14 COG: BH0263; COG1595 DNA-directed RNA polymerase specialized sigma; E=6e-16 PFAM: PF00776; Sigma-70 factor (ECF subfamily); E=6.8e-12.
  
     0.489
sigW
Probable RNA polymerase sigma factor sigW; PMID: 9274029 best DB hits: BLAST: pir:H70507; probable sigE protein - Mycobacterium tuberculosis; E=6e-14 gb:AAC45221.1; (U87307) extracytoplasmic function alternative; E=2e-13 gb:AAC45219.1; (U87308) extracytoplasmic function alternative; E=5e-13 COG: Rv1221; COG1595 DNA-directed RNA polymerase specialized sigma; E=6e-15 PFAM: PF00776; Sigma-70 factor (ECF subfamily); E=2.1e-09.
  
     0.489
cnrH
PMID: 8052622 best DB hits: BLAST: swissprot:P37978; CNRH_ALCEU RNA POLYMERASE SIGMA FACTOR CNRH; E=5e-04 pir:G83282; probable sigma-70 factor, ECF subfamily PA2896; E=0.008 pir:S74832; transcription initiation factor sigma E sll0856 -; E=0.055 COG: PA2896; COG1595 DNA-directed RNA polymerase specialized sigma; E=8e-04 PFAM: PF00776; Sigma-70 factor (ECF subfamily); E=0.028 PF00140; Sigma-70 factor; E=0.028.
  
     0.484
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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