STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
chd1Cryptic haloacid dehalogenase 1; PMID: 99429847 best DB hits: BLAST: embl:CAA06738.1; (AJ005843) cryptic haloacid dehalogenase 1; E=2e-31 embl:CAB61854.1; (AL133252) putative dehalogenase [Streptomyces; E=3e-24 pdb:1ZRN; Intermediate Structure Of L-2-Haloacid Dehalogenase; E=7e-20 COG: BH3587; COG0546 Predicted phosphatases; E=2e-09 PA0810; COG1011 Predicted hydrolases of the HAD superfamily; E=7e-07 DR2613; COG0637 Predicted phosphatase/phosphohexomutase; E=6e-06 PFAM: PF00702; haloacid dehalogenase-like hydrolas; E=8.2e-21. (274 aa)    
Predicted Functional Partners:
RB10172
Aldehyde dehydrogenase; PMID: 9369242 best DB hits: BLAST: gb:AAA64636.1; (U07235) aldehyde dehydrogenase [Mus musculus]; E=1e-163 gb:AAA51693.1; (M20456) aldehyde dehydrogenase [Homo sapiens]; E=1e-163 pir:DEHUE2; aldehyde dehydrogenase (NAD+) (EC 1.2.1.3) 2 precursor,; E=1e-162 COG: BH0539; COG1012 NAD-dependent aldehyde dehydrogenases; E=1e-156 PFAM: PF00171; Aldehyde dehydrogenase family; E=1.5e-240; Belongs to the aldehyde dehydrogenase family.
     
  0.900
RB12362
Peroxiredoxin; Best DB hits: BLAST: pir:S74867; hypothetical protein sll1159 - Synechocystis sp. (strain; E=2e-23 pir:T36936; hypothetical protein SCJ1.03c - Streptomyces coelicolor; E=1e-17 pir:E72332; thioredoxin peroxidase (EC 1.11.1.-) TM0780 [similarity]; E=1e-05 COG: sll1159; COG1225 Peroxiredoxins; E=2e-24 DR2242; COG0450 Thiol - alkyl hydroperoxide reductases; E=4e-04 bcp; COG1225 Peroxiredoxins; E=4e-04.
    0.720
RB4571
Conserved hypothetical protein; Best DB hits: BLAST: gb:AAD54003.1; AF088856_2 (AF088856) hypothetical protein; E=4e-20 embl:CAB69777.1; (AL137187) putative tetR-family transcriptional; E=6e-16 embl:CAB93063.1; (AL357432) putative transcriptional regulator; E=2e-14 COG: VCA0586; COG1309 Transcriptional regulator; E=1e-11 PFAM: PF00440; Bacterial regulatory proteins, tetR; E=5.4e-11.
 
   
 0.599
RB3630
Conserved hypothetical protein; PMID: 10984043 best DB hits: BLAST: pir:D83354; hypothetical protein PA2331 [imported] - Pseudomonas; E=7e-26 pir:B81134; macrophage infectivity potentiator-related protein; E=2e-19 pir:D81888; hypothetical protein NMA1203 [imported] - Neisseria; E=4e-18 COG: PA2331; COG2128 Uncharacterized ACR; E=6e-27.
 
     0.588
RB4572
Hypothetical protein.
       0.486
RB13146
Conserved hypothetical protein-putative xylosidase/arabinosidase; PMID: 8843436 best DB hits: BLAST: embl:CAB61805.1; (AL133236) hypothetical protein SCE65.17c; E=5e-41 ddbj:BAB05597.1; (AP001513) BH1878~unknown conserved protein; E=0.003 gb:AAB97967.1; (AF040720) xylosidasearabinosidase [Selenomonas; E=0.010; Belongs to the glycosyl hydrolase 43 family.
  
     0.457
ribD
PMID: 9068650 best DB hits: BLAST: pir:T50546; riboflavin bifunctional biosynthesis protein ribG; E=2e-56 swissprot:P50853; RIBD_ACTPL RIBOFLAVIN BIOSYNTHESIS PROTEIN RIBD; E=2e-56 ddbj:BAB05273.1; (AP001512) riboflavin specific; E=9e-52 COG: ribD_1; COG0117 Pyrimidine deaminase; E=1e-28 BH1554_2; COG1985 Pyrimidine reductase, riboflavin biosynthesis; E=6e-21 CPn0871_1; COG0117 Pyrimidine deaminase; E=1e-20 PFAM: PF00383; Cytidine and deoxycytidylate de; E=1.5e-31 PF01872; RibD C-terminal domain; E=4e-33.
     
 0.429
mip-2
Probable Mip; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.
 
     0.409
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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