STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB4702Probable lipase/esterase; PMID: 10509949 best DB hits: BLAST: pir:B75555; probable lipaseesterase - Deinococcus radiodurans; E=6e-08 swissprot:Q04457; EST1_CAEEL GUT ESTERASE PRECURSOR (NON-SPECIFIC; E=9e-06 pir:T32061; gut-specific carboxylesterase ges-1 - Caenorhabditis; E=9e-06 COG: DR0133; COG0657 Acetyl esterase; E=6e-09. (478 aa)    
Predicted Functional Partners:
RB12482
Probable lipase/esterase; PMID: 1907455 best DB hits: BLAST: pir:B75555; probable lipaseesterase - Deinococcus radiodurans; E=1e-19 pdb:1EVQ; A Chain A, The Crystal Structure Of The Thermophilic; E=6e-12 pir:H70731; probable esterase - Mycobacterium tuberculosis (strain; E=5e-11 COG: DR0133; COG0657 Acetyl esterase; E=1e-20 XF2260; COG1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases; E=1e-04 aes; COG0657 Acetyl esterase; E=5e-04.
 
     0.765
RB6725
Lipase; PMID: 9464382 best DB hits: BLAST: gb:AAC38151.1; (AF034088) lipase [Pseudomonas sp. B11-1]; E=4e-34 ddbj:BAA82510.1; (AB029896) esterase HDE [petroleum-degrading; E=3e-33 gb:AAB89533.1; (AE000985) carboxylesterase (estA) [Archaeoglobus; E=2e-30 COG: AF1716; COG0657 Acetyl esterase; E=2e-31 PFAM: PF00135; Carboxylesterase; E=0.75 PF00326; Prolyl oligopeptidase family; E=0.72 PF00561; alpha/beta hydrolase fold; E=0.27.
  
     0.648
RB11975
Polyketide synthase; PMID: 10662695 PMID: 10649995 best DB hits: BLAST: gb:AAF26921.1; AF210843_18 (AF210843) polyketide synthase [Sorangium; E=0.0 gb:AAF26923.1; AF210843_20 (AF210843) polyketide synthase [Sorangium; E=0.0 gb:AAF62883.1; AF217189_6 (AF217189) epoD [Sorangium cellulosum]; E=0.0 COG: BS_fabD; COG0331 (acyl-carrier-protein) S-malonyltransferase; E=7e-31 PA2965; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase I; E=3e-28 PA5234; COG0604 NADPH:quinone reductase and related Zn-dependent; E=2e-27 PFAM: PF00108; Thiolase, N-terminal domain; E=7.3e-07 PF00109; Beta-ketoacyl s [...]
  
 
 0.605
RB4703
Hypothetical protein.
       0.572
RB4704
Hypothetical protein.
       0.572
RB386
Saframycin Mx1 synthetase B; PMID: 8936303 best DB hits: BLAST: pir:T18551; saframycin Mx1 synthetase B - Myxococcus xanthus -----; E=1e-112 pir:T34918; polyketide synthase - Streptomyces coelicolor -----; E=1e-102 pir:H83343; probable non-ribosomal peptide synthetase PA2424; E=1e-101 COG: PA2424_1; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid; E=1e-102 Rv1529; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases; E=7e-83 Ta1189; COG0156 7-keto-8-aminopelargonate synthetase and related; E=6e-62 PFAM: PF00501; AMP-binding enzyme; E=2.2e-08 PF00550; Phosphopantetheine attac [...]
  
 
 0.556
RB2231
Hypothetical protein.
  
     0.539
RB10144
PMID: 1909424 best DB hits: BLAST: swissprot:P26223; XYNB_BUTFI ENDO-1,4-BETA-XYLANASE B (XYLANASE B); E=2e-18 prf:1718306A; xylanase [Butyrivibrio fibrisolvens]; E=2e-18 gb:AAK04528.1; AE006280_4 (AE006280) sugar hydrolase [Lactococcus; E=1e-17 COG: DR0821_2; COG0657 Acetyl esterase; E=6e-06 DR0165; COG1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases; E=0.004 PFAM: PF01738; Dienelactone hydrolase family; E=0.81 PF00561; alpha/beta hydrolase fold; E=0.0016.
  
     0.537
RB2103
Acyl-CoA synthetase; PMID: 9634230 best DB hits: BLAST: pir:T18551; saframycin Mx1 synthetase B - Myxococcus xanthus -----; E=1e-101 pir:H83343; probable non-ribosomal peptide synthetase PA2424; E=4e-96 gb:AAG02359.1; AF210249_18 (AF210249) peptide synthetase NRPS5-4-3; E=7e-93 COG: PA2424_1; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid; E=4e-97 Rv3826; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases; E=7e-82 VNG1339C; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid; E=9e-19 PFAM: PF00501; AMP-binding enzyme; E=1.7e-07 PF00550; Phosphopantetheine attachment sit; [...]
  
 
 0.498
RB4699
Conserved hypothetical protein; PMID: 7528875 best DB hits: BLAST: ddbj:BAB04561.1; (AP001510) BH0842~unknown conserved protein; E=2e-09 embl:CAB56146.1; (AL117669) putative large secreted protein; E=7e-07 embl:CAB91126.1; (AL355913) hypothetical protein SC5H4.14; E=0.17.
       0.497
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.