STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB4958Similar to adenylate cyclase; PMID: 9171404 best DB hits: BLAST: ddbj:BAA14001.1; (D89626) adenylate cyclase [Anabaena sp.]; E=0.018 pir:S75331; penicillin-binding protein 1B mrcB - Synechocystis sp; E=0.10 ddbj:BAB11326.1; (AB016886) gene_id:MCA23.11~unknown protein; E=0.14 COG: slr1710; COG0744 Membrane carboxypeptidase (penicillin-binding; E=0.010 PFAM: PF02590; Uncharacterized ACR, COG1576; E=0.23 PF00498; FHA domain; E=1.6e-09. (250 aa)    
Predicted Functional Partners:
RB1508
Probable n-terminal acetyltransferase; PMID: 3106324 best DB hits: BLAST: pir:D75017; n-terminal acetyltransferase PAB1098 - Pyrococcus abyssi; E=4e-05 pir:A71455; probable acetyltransferase - Pyrococcus horikoshii; E=2e-04 embl:CAA51674.1; (X73149) Nourseothricin acetyltransferase; E=3e-04 COG: PAB1098; COG0456 Acetyltransferases; E=4e-06 BS_yobR; COG0454 Histone acetyltransferase HPA2 and related; E=1e-04 PA4678; COG0456 Acetyltransferases; E=5e-04 PFAM: PF00583; Acetyltransferase (GNAT) family; E=3.8e-21.
  
     0.639
RB6417
Conserved hypothetical protein-putative FHA domain; PMID: 9634230 PMID: 7482699 best DB hits: BLAST: pir:B70700; hypothetical protein Rv0020c - Mycobacterium; E=8e-06 pir:T10015; hypothetical protein MLB1770.15c - Mycobacterium leprae; E=4e-05 ddbj:BAB20624.1; (AB052847) adenylate cyclase; E=0.001 COG: Rv0020c_2; COG1716 FHA-domain-containing proteins; E=4e-06 PFAM: PF00498; FHA domain; E=8.9e-17.
  
     0.626
RB2247
Conserved hypothetical protein; Best DB hits: BLAST: gb:AAG19229.1; (AE005019) Vng0754c [Halobacterium sp. NRC-1]; E=9e-06 gb:AAF75279.1; AF265353_1 (AF265353) byssal protein Dpfp1; E=0.21 ddbj:BAA94345.1; (AB035520) parchorin [Oryctolagus cuniculus]; E=0.50 PFAM: PF00089; Trypsin; E=0.58.
  
     0.620
RB7495
Conserved hypothetical protein-containing TPR-domains; PMID: 11932238 best DB hits: BLAST: gb:AAD38597.1; AF145622_1 (AF145622) BcDNA.GH04245 [Drosophila; E=6e-08 gb:AAG22339.1; (AE003787) Ogt gene product [alt 3] [Drosophila; E=6e-08 swissprot:P56558; OGT1_RAT UDP-N-ACETYLGLUCOSAMINE--PEPTIDE; E=9e-08 COG: MTH72; COG0457 TPR-repeat-containing proteins; E=9e-07 PFAM: PF00515; TPR Domain; E=0.017 PF00671; Iron/Ascorbate oxidoreductase; E=0.67 PF00515; TPR Domain; E=0.21.
  
 
 0.605
RB6045
Hypothetical protein-transmembrane prediction.
  
     0.593
comQ
Similar to general secretory pathway protein D; PMID: 10419967 best DB hits: BLAST: gb:AAK00351.1; AF329876_7 (AF329876) putative outer membrane protein; E=2e-10 embl:CAA32520.1; (X14336) gene IV product [Bacteriophage I2-2]; E=2e-08 pir:D82816; fimbrial assembly protein XF0373 [imported] - Xylella; E=4e-05 COG: XF0373; COG1450 General secretory pathway protein D; E=3e-06 PFAM: PF00263; Bacterial type II and III secretion; E=5.3e-20; Belongs to the bacterial secretin family.
  
    0.591
RB6127
Hypothetical protein-signal peptide prediction; Best DB hits: PFAM: PF01842; ACT domain; E=0.55 PF00515; TPR Domain; E=0.051.
  
     0.591
RB4960
Conserved hypothetical protein; Best DB hits: BLAST: ddbj:BAB07003.1; (AP001518) BH3284~unknown conserved protein; E=2e-51 pir:D69999; conserved hypothetical protein ytqA - Bacillus subtilis; E=3e-48 gb:AAK06364.1; AE006455_10 (AE006455) HYPOTHETICAL PROTEIN; E=1e-46 COG: BH3284; COG1242 Uncharacterized FeS oxidoreductases; E=2e-52 MJ1136; COG1243 ELP3 component of the RNA polymerase II complex,; E=2e-07 BS_hemN; COG0635 Coproporphyrinogen III oxidase and related FeS; E=2e-05.
       0.579
flgI-2
Best DB hits: BLAST: pir:G72242; flagellar P-ring protein - Thermotoga maritima (strain; E=9e-07 gb:AAG09321.1; (AF178757) CpcF [Nostoc sp. PCC 7120]; E=0.10 pir:T44927; hypothetical protein orf398 [imported] - Anabaena sp; E=0.47 COG: TM1539; COG1706 Flagellar basal-body P-ring protein; E=9e-08.
  
     0.537
RB5968
Best DB hits: BLAST: pir:B72234; RNA polymerase sigma-E factor - Thermotoga maritima; E=0.42 gb:AAC14121.1; (AF056199) sigma factor E [Streptomyces; E=0.80 PFAM: PF00140; Sigma-70 factor; E=4.9e-05 PF00196; Bacterial regulatory proteins,; E=0.19.
  
    0.536
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.