STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
alkADNA-3-methyladenine glycosidase; PMID: 8921872 PMID: 91092284 PMID: 89024568 best DB hits: BLAST: pir:T08409; DNA-3-methyladenine glycosidase I homolog F18B3.160 -; E=9e-20 gb:AAD39589.1; AC007858_3 (AC007858) This gene is a member of PF; E=2e-19 ddbj:BAB05468.1; (AP001513) DNA-3-methyladenine glycosidase; E=4e-19 COG: BH1749; COG0122 3-Methyladenine DNA glycosylase; E=4e-20. (207 aa)    
Predicted Functional Partners:
RB2794
Deoxyribonuclease gamma [precursor]; PMID: 9665719 best DB hits: BLAST: gb:AAC64266.1; (AF059612) deoxyribonuclease gamma [Xenopus; E=1e-19 gb:AAB00496.1; (L40823) DNL1L gene product [Homo sapiens]; E=5e-17 gb:AAB17022.1; (U06846) XIB [Homo sapiens]; E=7e-17 PFAM: PF01181; Deoxyribonuclease I (DNase I); E=1.3e-10.
  
 0.708
exoA
Exodeoxyribonuclease; PMID: 1708495 best DB hits: BLAST: swissprot:P37454; EXOA_BACSU EXODEOXYRIBONUCLEASE ----- pir:; E=7e-78 pir:F64710; exodeoxyribonuclease - Helicobacter pylori (strain; E=3e-72 pir:C71809; exodeoxyribonuclease - Helicobacter pylori (strain J99); E=2e-71 COG: BS_exoA; COG0708 Exonuclease III; E=7e-79 PFAM: PF01181; Deoxyribonuclease I (DNase I); E=0.25 PF01260; AP endonuclease family 1; E=2e-108.
  
 0.708
dnl1
PMID: 9469931 best DB hits: BLAST: swissprot:P00639; DRN1_BOVIN DEOXYRIBONUCLEASE I PRECURSOR (DNASE; E=6e-11 pdb:3DNI; Deoxyribonuclease I (Dnase I) (E.C.3.1.21.1) -----; E=6e-11 pdb:1ATN; D Chain D, Deoxyribonuclease I Complex With Actin; E=9e-11 PFAM: PF01181; Deoxyribonuclease I (DNase I); E=0.053.
  
 0.708
RB5001
Hypothetical protein.
       0.543
RB5003
High affinity ammonium transporter; PMID: 8062823 PMID: 96214991 PMID: 8062822 best DB hits: BLAST: swissprot:P72935; YA17_SYNY3 PUTATIVE AMMONIUM TRANSPORTER SLL1017; E=1e-70 gb:AAF15904.1; AF208160_1 (AF208160) high affinity ammonium; E=1e-56 swissprot:P54147; Y108_SYNY3 PUTATIVE AMMONIUM TRANSPORTER SLL0108; E=1e-55 COG: sll1017; COG0004 Ammonia permeases; E=1e-71 PFAM: PF00909; Ammonium Transporter Family; E=7.6e-157.
       0.543
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.527
recA
RecA protein (Recombinase A); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
    
 
 0.477
rho
Probable transcription termination factor; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.
       0.462
RB1606
O-6-methylguanine-DNA methyltransferase (ada); PMID: 8156986 best DB hits: BLAST: pir:H83380; O6-methylguanine-DNA methyltransferase PA2118 [imported]; E=9e-29 gb:AAA23413.1; (M10315) Ada polyprotein [Escherichia coli]; E=7e-26 pdb:1SFE; Ada O6-Methylguanine-Dna Methyltransferase From; E=7e-26 COG: PA2118_2; COG0350 Methylated DNA-protein cysteine methyltransferase; E=5e-29 PFAM: PF01035; 6-O-methylguanine DNA methyltr; E=3.9e-33.
  
  
 0.448
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
     
 0.412
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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