STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glnB-3Nitrogen regulatory protein P-II; PMID: 1702507 best DB hits: BLAST: pir:A72380; nitrogen regulatory protein P-II - Thermotoga maritima; E=4e-21 swissprot:P21193; GLNB_AZOBR NITROGEN REGULATORY PROTEIN P-II; E=8e-17 embl:CAA63238.1; (X92496) PII-like protein Pz [Azospirillum; E=1e-16 COG: TM0403; COG0347 Nitrogen regulatory protein PII; E=4e-22 PFAM: PF00543; Nitrogen regulatory protein P-II; E=2.7e-27. (158 aa)    
Predicted Functional Partners:
RB5003
High affinity ammonium transporter; PMID: 8062823 PMID: 96214991 PMID: 8062822 best DB hits: BLAST: swissprot:P72935; YA17_SYNY3 PUTATIVE AMMONIUM TRANSPORTER SLL1017; E=1e-70 gb:AAF15904.1; AF208160_1 (AF208160) high affinity ammonium; E=1e-56 swissprot:P54147; Y108_SYNY3 PUTATIVE AMMONIUM TRANSPORTER SLL0108; E=1e-55 COG: sll1017; COG0004 Ammonia permeases; E=1e-71 PFAM: PF00909; Ammonium Transporter Family; E=7.6e-157.
 
 
 0.927
RB10892
Putative ammonium transporter; PMID: 8590279 best DB hits: BLAST: swissprot:P54148; Y537_SYNY3 PUTATIVE AMMONIUM TRANSPORTER SLL0537; E=9e-88 swissprot:P54147; Y108_SYNY3 PUTATIVE AMMONIUM TRANSPORTER SLL0108; E=1e-70 gb:AAB89503.1; (AE000982) ammonium transporter (amt-2); E=2e-66 COG: sll0537; COG0004 Ammonia permeases; E=8e-89 VC1084; COG0642 Sensory transduction histidine kinases; E=2e-33 MTH661; COG0004 Ammonia permeases; E=1e-32 PFAM: PF00909; Ammonium Transporter Family; E=1.9e-133 PF00512; His Kinase A (phosphoacceptor; E=6.1e-05 PF02518; Histidine kinase-, DNA gyrase; E=3.7e-25.
 
 
 0.864
amtB
Ammonium transporter; Best DB hits: BLAST: gb:AAK00343.1; AF329498_3 (AF329498) ammonium transporter AmtB; E=4e-82 gb:AAC38548.1; (AF005275) AmtB [Azospirillum brasilense]; E=3e-81 embl:CAA12410.1; (AJ225126) ammonium transporter, AmtB; E=4e-77 COG: PA5287; COG0004 Ammonia permeases; E=2e-76 PFAM: PF00909; Ammonium Transporter Family; E=1.5e-154.
 
 
 0.851
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
    
 
 0.836
mutY
A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.
      
 0.695
speD
Probable S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
      
 0.610
axeA
Probable acetyl xylan esterase AxeA; PMID: 10473406 PMID: 9274014 best DB hits: BLAST: pir:T05414; protein kinase homolog F28A23.20 - Arabidopsis thaliana; E=9e-17 gb:AAG36766.1; AF180369_1 (AF180369) acetyl xylan esterase AxeA; E=3e-14 pir:T47558; hypothetical protein F8J2.180 - Arabidopsis thaliana; E=5e-13.
       0.598
RB5008
Hypothetical protein-transmembrane region and signal peptide prediction; Best DB hits: PFAM: PF00150; Cellulase (glycosyl hydrolase famil; E=0.26; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
       0.598
glnD
Uridylyltransferase/uridylyl-removing enzyme glnD; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
 
 
 
 0.586
lnt
Probable apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.
      
 0.580
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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