STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB5152ABC transporter, ATP-binding protein; PMID: 2229036 best DB hits: BLAST: swissprot:P33982; YHBG_AZOCA PROBABLE ABC TRANSPORTER ATP-BINDING; E=2e-66 gb:AAA80299.1; (U23471) ABC-type permease homolog [Rhizobium; E=1e-64 swissprot:P25885; YHBG_RHIME PROBABLE ABC TRANSPORTER ATP-BINDING; E=7e-63 COG: DR2134; COG1137 ABC-type (unclassified) transport system, ATPase; E=2e-61 PA1071; COG0411 High-affinity branched-chain amino acid transport; E=1e-37 MTH1370; COG1131 ABC-type multidrug transport system, ATPase; E=3e-35 PFAM: PF00005; ABC transporter; E=3.8e-59. (317 aa)    
Predicted Functional Partners:
RB5826
Conserved hypothetical protein-putative permease; PMID: 8905231 best DB hits: BLAST: pir:S75996; hypothetical protein - Synechocystis sp. (strain PCC; E=2e-05 pir:S77272; hypothetical protein slr0882 - Synechocystis sp. (strain; E=0.023 pir:F72217; conserved hypothetical protein - Thermotoga maritima; E=0.13 COG: sll0496; COG0795 Predicted permeases; E=2e-06.
 
 
 0.990
RB2209
Hypothetical protein-signal peptide and transmembrane prediction.
   
 0.979
lpdX
UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
 
  
 0.796
lpxA
acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
  
 0.791
lpxB
lipid-A-disaccharide synthetase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
   
 0.779
tolQ-2
Probable tolQ protein; PMID: 8331075 PMID: 10348868 PMID: 8921895 best DB hits: BLAST: pir:G83274; probable tolQ-type transport protein PA2983 [imported] -; E=7e-13 pir:H71686; tolQ protein (tolQ) RP309 - Rickettsia prowazekii; E=1e-10 pir:G82187; biopolymer transport protein ExbB-related protein VC1547; E=1e-10 COG: PA2983; COG0811 Biopolymer transport proteins; E=7e-14 PFAM: PF01618; MotA/TolQ/ExbB proton channel famil; E=4e-28.
  
   
 0.758
lepB
PMID: 2202591 best DB hits: BLAST: pir:C82073; signal peptidase I VC2462 [imported] - Vibrio cholerae; E=3e-07 pir:H83550; signal peptidase I PA0768 [imported] - Pseudomonas; E=3e-06 swissprot:P23697; LEP_SALTY SIGNAL PEPTIDASE I (SPASE I) (LEADER; E=3e-06 COG: VC2462; COG0681 Signal peptidase I; E=3e-08 PFAM: PF00461; Signal peptidase I; E=0.00013; Belongs to the peptidase S26 family.
       0.755
ilvA
Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
       0.745
exbB
Probable biopolymer transport ExbB-related protein; PMID: 8437515 best DB hits: BLAST: pir:D82726; conserved hypothetical protein XF1079 [imported] -; E=8e-21 pir:G83274; probable tolQ-type transport protein PA2983 [imported] -; E=4e-19 embl:CAB50918.1; (AJ243354) hypothetical protein [Pseudomonas; E=8e-16 COG: XF1079; COG0811 Biopolymer transport proteins; E=8e-22 PFAM: PF01618; MotA/TolQ/ExbB proton channel famil; E=3.1e-21.
  
   
 0.740
tolQ-3
PMID: 10984043 best DB hits: BLAST: pir:G83274; probable tolQ-type transport protein PA2983 [imported] -; E=1e-15 pir:D82726; conserved hypothetical protein XF1079 [imported] -; E=4e-10 gb:AAC69453.1; (AF047974) TolR [Vibrio cholerae]; E=1e-09 COG: PA2983; COG0811 Biopolymer transport proteins; E=1e-16 PFAM: PF01618; MotA/TolQ/ExbB proton channel famil; E=1.9e-20.
  
   
 0.737
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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