STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB5295Heparan N-sulfatase; PMID: 96083602 best DB hits: BLAST: prf:2204388A; sulphamidase [Homo sapiens]; E=6e-47 gb:AAG17207.1; AF217204_1 (AF217204) heparan sulfate sulfamidase; E=6e-45 gb:AAF29467.1; (AF156255) N-sulfoglucosamine sulfohydrolase [Mus; E=4e-44 COG: Rv0296c; COG3119 Arylsulfatase A and related enzymes; E=6e-38 VC2600; COG3083 Predicted hydrolase of alkaline phosphatase; E=9e-05 VNG0061C; COG3119 Arylsulfatase A and related enzymes; E=0.006 PFAM: PF00884; Sulfatase; E=1.4e-43. (493 aa)    
Predicted Functional Partners:
RB5294
Probable sulfatase atsG; PMID: 9634230 best DB hits: BLAST: pir:F70837; probable sulfatase (EC 3.1.6.-) atsG - Mycobacterium; E=1e-37 prf:2204388A; sulphamidase [Homo sapiens]; E=4e-23 gb:AAG41945.1; AF304053_1 (AF304053) heparan N-sulfatase [Mus; E=8e-23 COG: Rv0296c; COG3119 Arylsulfatase A and related enzymes; E=1e-38 PFAM: PF00884; Sulfatase; E=1.5e-28.
 
    
0.826
RB5288
Best DB hits: BLAST: embl:CAB45032.1; (AL078635) putative large multi-functional; E=3e-22 embl:CAB58265.1; (AL121849) putative multi-domain protein; E=9e-19 pir:T36423; probable large, multifunctional secreted protein -; E=0.002.
  
    0.694
RB5290
Probable NADH-dependent dehydrogenase; Best DB hits: BLAST: pir:T34927; probable oxidoreductase - Streptomyces coelicolor; E=2e-07 gb:AAC23913.1; (AF039207) NADH-dependent dehydrogenase homolog; E=6e-07 pir:B72359; lipopolysaccharide biosynthesis protein BplA -; E=3e-05 COG: TM0585; COG0673 Predicted dehydrogenases and related proteins; E=3e-06 PFAM: PF01408; Oxidoreductase family, NAD-bindi; E=3.2e-18.
  
    0.692
RB5298
Hypothetical protein.
       0.572
acrB
Acriflavine resistance protein B; PMID: 8905231 PMID: 8407802 PMID: 7651136 best DB hits: BLAST: pir:F83335; RND multidrug efflux transporter MexF PA2494 [imported] -; E=0.0 pir:T30830; hypothetical protein mexF - Pseudomonas aeruginosa -----; E=0.0 pir:D83206; probable RND efflux transporter PA3522 [imported] -; E=0.0 COG: PA2494; COG0841 Cation/multidrug efflux pump; E=0.0 PFAM: PF00873; AcrB/AcrD/AcrF family; E=0; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
      
 0.550
RB950
Amino acid transporter; PMID: 3146645 best DB hits: BLAST: swissprot:Q10858; YJ99_MYCTU HYPOTHETICAL 45.3 KDA TRANSPORT; E=2e-23 embl:CAB76881.1; (AL159139) putative amino acid transporter; E=2e-16 pir:G82809; amino acid transporter XF0408 [imported] - Xylella; E=3e-15 COG: Rv1999c; COG0531 Amino acid transporters; E=2e-24 BS_gabP; COG1113 Gamma-aminobutyrate and related permeases; E=2e-06 Rv3253c; COG0531 Amino acid transporters; E=4e-06 PFAM: PF00324; Amino acid permease; E=0.00042.
      
 0.540
RB5281
N-acetylgalactosamine 6-sulfatase (GALNS); PMID: 8020961 best DB hits: BLAST: ddbj:BAA04535.1; (D17629) N-acetylgalactosamine 6-sulfate; E=6e-47 gb:AAF63858.1; (AF112242) N-acetylgalactosamine-6-sulfate; E=8e-46 pir:KJHUAB; N-acetylgalactosamine-4-sulfatase (EC 3.1.6.12); E=1e-44 COG: ydeN; COG3119 Arylsulfatase A and related enzymes; E=1e-41 TM1703; COG1368 Phosphoglycerol transferase and related proteins,; E=7e-04 PAB0793; COG2194 Predicted membrane-associated, metal-dependent; E=0.003 PFAM: PF00884; Sulfatase; E=2.1e-109.
 
    
0.525
RB5282
PMID: 10809675 best DB hits: BLAST: gb:AAF72520.1; AF248951_1 (AF248951) mucin-desulfating sulfatase; E=2e-32 swissprot:P31447; YIDJ_ECOLI PUTATIVE SULFATASE YIDJ -----; E=4e-27 gb:AAG58881.1; AE005599_13 (AE005599) putative sulfatase; E=8e-26 COG: yidJ; COG3119 Arylsulfatase A and related enzymes; E=3e-28 PAB0793; COG2194 Predicted membrane-associated, metal-dependent; E=0.005 PFAM: PF00884; Sulfatase; E=1.1e-26.
 
    
0.520
RB5285
Similar to collagen alpha-2 (XI) chain; PMID: 8981332 best DB hits: BLAST: gb:AAA67751.1; (U16789) putative collagen alpha-2 (XI) chain [Mus; E=0.024 gb:AAA67752.1; (U16790) putative collagen alpha-2 (XI) chain [Mus; E=0.024 pir:A55576; collagen alpha 2(XI) chain precursor, long form - mouse; E=0.024.
       0.508
RB5286
Hypothetical protein-signal peptide and transmembrane prediction.
       0.508
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.