STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB5482Probable response regulator; PMID: 7699720 best DB hits: BLAST: ddbj:BAA14000.1; (D89625) adenylate cyclase [Anabaena sp.]; E=2e-12 pir:T17197; adenylate cyclase homolog - Spirulina platensis -----; E=8e-12 gb:AAB89775.1; (AE001001) response regulator [Archaeoglobus; E=7e-10 COG: AF1473; COG0784 CheY-like receiver domains; E=7e-11 slr0115; COG0745 Response regulators consisting of a CheY-like; E=2e-10 sll1555_1; COG0784 CheY-like receiver domains; E=6e-10 PFAM: PF00072; Response regulator receiver doma; E=2.3e-16. (218 aa)    
Predicted Functional Partners:
RB5479
Probable sensory transduction histidine kinase; PMID: 3142862 best DB hits: BLAST: swissprot:P23545; PHOR_BACSU ALKALINE PHOSPHATASE SYNTHESIS SENSOR; E=1e-28 pir:S75514; sensory transduction histidine kinase slr1324 -; E=2e-27 pir:E83529; sensorresponse regulator hybrid PA0928 [imported] -; E=6e-25 COG: BS_phoR_3; COG0642 Sensory transduction histidine kinases; E=1e-29 PFAM: PF00072; Response regulator receiver do; E=4.5e-14 PF00512; His Kinase A (phosphoacceptor); E=6.3e-16 PF02518; Histidine kinase-, DNA gyrase; E=5.3e-31.
 
 
 0.939
RB10924
Probable sensor/response regulator hybrid; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 
 0.903
RB4511
Sensory transduction histidine kinase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 
 0.889
flgE
Flagellar hook protein FlgE; PMID: 10368149 best DB hits: BLAST: gb:AAD24206.1; AF049342_4 (AF049342) flagellar hook protein FlgE; E=8e-22 gb:AAA61738.1; (U19712) flagellar hook polypeptide [Borrelia; E=1e-21 gb:AAA91361.1; (U12870) flagellar distal rod protein [Borrelia; E=3e-21 COG: BB0283; COG1749 Flagellar basal body and hook proteins; E=5e-22 PFAM: PF00460; Flagella basal body rod protein; E=3.7e-10.
  
  
 0.799
phoB
Probable regulatory components of sensory transduction system; PMID: 8905231 best DB hits: BLAST: embl:CAA11074.1; (AJ223073) phosphate regulatory protein; E=3e-11 pir:B70152; response regulatory protein (rrp-1) homolog - Lyme; E=1e-10 gb:AAD30120.2; (AF135389) DNA binding response regulator RpaA; E=2e-10 COG: BB0419_1; COG0784 CheY-like receiver domains; E=1e-11 slr0115; COG0745 Response regulators consisting of a CheY-like; E=2e-10 slr1305_1; COG0784 CheY-like receiver domains; E=3e-09 PFAM: PF00072; Response regulator receiver doma; E=1.4e-18.
  
 
   0.754
hydH-3
Sensor protein HYDH; PMID: 2666400 best DB hits: BLAST: swissprot:P14377; HYDH_ECOLI SENSOR PROTEIN HYDH ----- pir:; E=5e-19 gb:AAG59200.1; AE005632_1 (AE005632) sensor kinase for HydG,; E=6e-18 swissprot:P07168; VIRA_AGRT6 WIDE HOST RANGE VIRA PROTEIN (WHR; E=6e-18 COG: hydH; COG0642 Sensory transduction histidine kinases; E=5e-20 PFAM: PF00512; His Kinase A (phosphoacceptor) doma; E=1.1e-06 PF02518; Histidine kinase-, DNA gyrase B-, p; E=4e-35.
  
 
   0.749
RB12326
Sensory histidine protein kinase; PMID: 11406410 best DB hits: BLAST: gb:AAA98756.1; (L29642) sensor kinase [Pseudomonas fluorescens]; E=2e-45 pir:F83153; probable two-component sensor PA3946 [imported] -; E=3e-36 pir:E83265; probable two-component sensor PA3044 [imported] -; E=2e-35 COG: PA3044; COG0642 Sensory transduction histidine kinases; E=2e-36 PFAM: PF01590; GAF domain; E=3.2e-20 PF00989; PAS domain; E=1.2e-07 PF00512; His Kinase A (phosphoacceptor) d; E=4.8e-16.
 
 
 0.727
RB6818
PMID: 9665876 best DB hits: BLAST: pir:D71379; probable sensory transduction histidine kinase -; E=5e-23 embl:CAB64771.1; (AJ007794) kin1 [Bacillus cereus] -----; E=1e-21 pir:B69863; two-component sensor histidine kinase homolog ykrQ -; E=2e-21 COG: BS_ykrQ_3; COG0642 Sensory transduction histidine kinases; E=2e-22 PFAM: PF00512; His Kinase A (phosphoacceptor) doma; E=6.1e-12 PF02518; Histidine kinase-, DNA gyrase B-, p; E=8.6e-32.
  
 
   0.707
RB6217
Putative response regulator; PMID: 10376842 best DB hits: BLAST: gb:AAD28578.1; AF121341_2 (AF121341) putative response regulator; E=7e-27 gb:AAA87378.1; (L42554) pleD gene product [Caulobacter; E=3e-21 pir:S74913; sensory transduction system regulatory protein slr1400 -; E=4e-21 COG: slr1400_1; COG0784 CheY-like receiver domains; E=4e-20 slr0115; COG0745 Response regulators consisting of a CheY-like; E=2e-19 VC0622_4; COG0784 CheY-like receiver domains; E=4e-19 PFAM: PF00072; Response regulator receiver doma; E=3.1e-37.
  
 
   0.705
RB8873
PMID: 7984107 best DB hits: BLAST: pir:S75136; sensory transduction histidine kinase slr2104 -; E=2e-56 pir:S75525; sensory transduction histidine kinase sll1228 -; E=4e-50 pir:E82198; sensor histidine kinaseresponse regulator VC1445; E=5e-46 COG: VC1349_2; COG0642 Sensory transduction histidine kinases; E=2e-43 PFAM: PF00785; PAC motif; E=0.00017 PF00512; His Kinase A (phosphoacceptor; E=1.1e-25 PF02518; Histidine kinase-, DNA gyrase; E=8.9e-44.
 
 
 0.688
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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