STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB5495Conserved hypothetical protein-putative multidrug resistance efflux pump; Best DB hits: BLAST: pir:A83342; conserved hypothetical protein PA2430 [imported] -; E=4e-07 swissprot:P32716; YJCR_ECOLI HYPOTHETICAL 36.9 KDA PROTEIN IN; E=2e-05 gb:AAG59280.1; AE005641_5 (AE005641) putative membrane protein; E=2e-05 COG: PA2430; COG1566 Multidrug resistance efflux pump; E=4e-08 HIN0311; COG0845 Membrane-fusion protein; E=0.002 PFAM: PF00529; HlyD family secretion protein; E=0.00042. (569 aa)    
Predicted Functional Partners:
RB5490
Best DB hits: BLAST: pir:F82263; probable multidrug resistance protein VC0914 [imported] -; E=1e-47 pir:H82300; probable multidrug resistance protein VC0629 [imported] -; E=6e-47 pir:F71727; acriflavin resistance protein D (acrD) RP170 - Rickettsia; E=3e-45 COG: VC0914; COG0841 Cation/multidrug efflux pump; E=1e-48 PFAM: PF00873; AcrB/AcrD/AcrF family; E=1.8e-14; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
     0.944
RB832
Cation/multidrug efflux pump; PMID: 8407802 best DB hits: BLAST: pir:G64595; acriflavine resistance protein - Helicobacter pylori; E=8e-52 gb:AAC14433.1; (AF059041) RND pump protein [Helicobacter pylori]; E=2e-51 pir:F82171; transporter, AcrBD/F family VC1673 [imported] - Vibrio; E=6e-44 COG: HP0607; COG0841 Cation/multidrug efflux pump; E=8e-53 PFAM: PF00873; AcrB/AcrD/AcrF family; E=5.9e-08; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
     0.771
RB11154
PMID: 10984043 best DB hits: BLAST: pir:A83330; probable RND efflux membrane fusion protein precursor; E=2e-06 gb:AAG57137.1; AE005434_1 (AE005434) putative membrane protein; E=2e-06 ddbj:BAA15928.1; (D90845) Membrane fusion protein MtrC precursor; E=4e-06 COG: PA2528; COG0845 Membrane-fusion protein; E=2e-07 PA3892; COG1566 Multidrug resistance efflux pump; E=1e-05 VC0628; COG0845 Membrane-fusion protein; E=4e-05 PFAM: PF00529; HlyD family secretion protein; E=4.2e-07; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
     0.755
czcA
PMID: 2678100 best DB hits: BLAST: pir:H82300; probable multidrug resistance protein VC0629 [imported] -; E=3e-51 pir:S76433; cation efflux system protein czcA-2 - Synechocystis sp; E=4e-42 pir:G64595; acriflavine resistance protein - Helicobacter pylori; E=4e-41 COG: VC0629; COG0841 Cation/multidrug efflux pump; E=3e-52 PFAM: PF00873; AcrB/AcrD/AcrF family; E=1e-43; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
     0.754
ibeB
PMID: 10225861 best DB hits: BLAST: pir:A83347; probable outer membrane protein PA2391 [imported] -; E=1e-24 pir:F83329; probable outer membrane lipoprotein precursor PA2525; E=2e-23 gb:AAD05185.1; (AF110185) unknown [Burkholderia pseudomallei]; E=4e-23 COG: PA2391; COG1538 Outer membrane protein; E=1e-25 PFAM: PF02321; Outer membrane efflux protein; E=1.3e-18.
  
   0.654
RB5498
Hypothetical protein.
       0.572
RB1125
PMID: 8181764 best DB hits: BLAST: pir:H82381; toxin secretion ATP-binding protein VCA1084 [imported] -; E=2e-12 pir:S75806; hemolysin secretion protein hlyB - Synechocystis sp; E=6e-12 gb:AAD21059.1; (AF119150) RtxB protein [Vibrio cholerae]; E=6e-12 COG: VCA1084; COG2274 ABC-type bacteriocin/lantibiotic exporters, contain; E=2e-13 sll1180_2; COG2274 ABC-type bacteriocin/lantibiotic exporters,; E=5e-13 VC1448; COG1132 ABC-type multidrug/protein/lipid transport system,; E=6e-13 PFAM: PF00664; ABC transporter transmembrane re; E=0.046 PF00005; ABC transporter; E=6.8e-06.
  
 
 0.428
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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