STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB5597Hypothetical protein-signal peptide prediction. (170 aa)    
Predicted Functional Partners:
RB5595
Hypothetical protein.
       0.689
hisI-2
Probable phosphoribosyl-ATP pyrophosphatase; PMID: 3062174 best DB hits: BLAST: swissprot:O30723; HIS2_RHOCA PHOSPHORIBOSYL-ATP PYROPHOSPHATASE; E=2e-10 swissprot:P26722; HIS2_AZOBR PHOSPHORIBOSYL-ATP PYROPHOSPHATASE; E=6e-08 pir:D81178; phosphoribosyl-ATP cyclohydrolase NMB0603 [imported] -; E=8e-08 COG: NMB0603; COG0140 Phosphoribosyl-ATP pyrophosphohydrolase; E=8e-09 PFAM: PF01503; Phosphoribosyl-ATP pyrophosphohydrol; E=9.2e-30.
       0.689
RB5593
Serine/threonine-protein kinase; PMID: 7768349 best DB hits: BLAST: gb:AAF73695.1; (AE002226) serinethreonine-protein kinase; E=7e-39 pir:G71532; probable threoninetyrosine-specific protein kinase (EC; E=3e-38 pir:C72120; st protein kinase - Chlamydophila pneumoniae (strain; E=4e-37 COG: CT301_1; COG0515 Serine/threonine protein kinases; E=3e-39 PFAM: PF00069; Protein kinase domain; E=2.2e-27 PF00515; TPR Domain; E=0.89 PF02018; Cellulose binding domain; E=0.037.
       0.515
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
       0.479
RB5604
Hypothetical protein.
       0.449
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.