STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB5655Probable transcription regulator; PMID: 3413113 best DB hits: BLAST: swissprot:Q9X725; OXYR_ERWCH HYDROGEN PEROXIDE-INDUCIBLE GENES; E=1e-25 swissprot:P71318; OXYR_ERWCA HYDROGEN PEROXIDE-INDUCIBLE GENES; E=1e-25 swissprot:P44418; OXYR_HAEIN HYDROGEN PEROXIDE-INDUCIBLE GENES; E=3e-25 COG: HI0571; COG0583 Transcriptional regulator; E=2e-26 PFAM: PF00126; Bacterial regulatory helix-turn-heli; E=9.6e-37; Belongs to the LysR transcriptional regulatory family. (325 aa)    
Predicted Functional Partners:
RB3702
PMID: 10567266 best DB hits: BLAST: pir:D75588; transcription regulator, HTH_1 family - Deinococcus; E=1e-15 swissprot:Q04778; ALSR_BACSU ALS OPERON REGULATORY PROTEIN -----; E=3e-15 pir:A83017; probable transcription regulator PA5029 [imported] -; E=6e-15 COG: DRA0336; COG0583 Transcriptional regulator; E=1e-16 PFAM: PF00126; Bacterial regulatory helix-turn-heli; E=1.7e-25; Belongs to the LysR transcriptional regulatory family.
  
     0.769
gltB
Glutamate synthase [NADPH] large chain; PMID: 2643092 PMID: 3326786 best DB hits: BLAST: swissprot:Q06434; GLSF_ANTSP FERREDOXIN-DEPENDENT GLUTAMATE SYNTHASE; E=0.0 swissprot:P23225; GLSF_MAIZE FERREDOXIN-DEPENDENT GLUTAMATE; E=0.0 swissprot:Q03460; GLSN_MEDSA GLUTAMATE SYNTHASE [NADH], CHLOROPLAST; E=0.0 COG: sll1502_2; COG0069 Glutamate synthetase domain 2; E=0.0 sll1502_1; COG0067 Glutamate synthetase domain 1; E=1e-118 PFAM: PF01645; Conserved region in glutamate; E=5.5e-235 PF01493; Domain of unknown function DU; E=4.2e-95.
  
  
 0.763
RB3549
Probable lactose operon transcription activator; PMID: 9573174 best DB hits: BLAST: ddbj:BAB05677.1; (AP001513) BH1958~unknown conserved protein; E=1e-07 swissprot:O33813; LACR_STAXY LACTOSE OPERON TRANSCRIPTION; E=4e-07 ddbj:BAB07561.1; (AP001520) two-component response regulator; E=6e-07 COG: BH1958; COG2207 AraC-type DNA-binding domain-containing proteins; E=1e-08 BH0394; COG2169 Adenosine deaminase; E=2e-06 PA2337; COG2207 AraC-type DNA-binding domain-containing proteins; E=3e-06 PFAM: PF00165; Bacterial regulatory helix-turn-heli; E=3.7e-20.
  
  
 0.455
gltD
NADH-glutamate synthase small chain; PMID: 2643092 PMID: 3326786 best DB hits: BLAST: ddbj:BAA12742.1; (D85230) small subunit of NADH-dependent; E=1e-163 pir:T49818; probable glutamate synthase (NADPH) [imported] -; E=1e-162 pir:S74625; NADH-glutamate synthase small chain gltD - Synechocystis; E=1e-161 COG: sll1027; COG0493 NADPH-dependent glutamate synthase beta chain and; E=1e-162 PFAM: PF01494; FAD binding domain; E=0.013 PF02254; KTN NAD-binding domain; E=0.036 PF00984; UDP-glucose/GDP-mannose dehydr; E=0.28.
   
 
 0.451
RB5657
Conserved hypothetical protein; Best DB hits: BLAST: gb:AAB81983.1; (AF025662) unknown [Vibrio cholerae]; E=7e-18 ddbj:BAB02723.1; (AB022216) gene_id:MGD8.2~unknown protein; E=1e-11 pir:T09703; pop3 protein - western balsam poplar x cottonwood; E=5e-08.
     
 0.419
iuvY
Probable transcriptional activator protein ilvY; PMID: 10588699 PMID: 9556617 best DB hits: BLAST: swissprot:P05827; ILVY_ECOLI TRANSCRIPTIONAL ACTIVATOR PROTEIN; E=1e-05 pir:S30671; ilvC activator - Escherichia coli; E=1e-05 gb:AAG58968.1; AE005608_9 (AE005608) positive regulator for ilvC; E=1e-05 COG: ilvY; COG0583 Transcriptional regulator; E=9e-07 PFAM: PF00126; Bacterial regulatory helix-turn-heli; E=6.1e-15; Belongs to the LysR transcriptional regulatory family.
  
     0.413
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.