STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB5720Predicted amidohydrolase; PMID: 7987228 best DB hits: BLAST: pir:C75051; hydrolase related PAB1449 - Pyrococcus abyssi (strain; E=5e-28 pir:C71109; hypothetical protein PH0642 - Pyrococcus horikoshii; E=7e-27 pir:B83387; hypothetical protein PA2074 [imported] - Pseudomonas; E=2e-22 COG: PAB1449; COG0388 Predicted amidohydrolase; E=5e-29 PFAM: PF00795; Carbon-nitrogen hydrolase; E=8e-48. (314 aa)    
Predicted Functional Partners:
RB1732
Beta-alanine synthetase; PMID: 10910347 best DB hits: BLAST: pir:H82556; beta-alanine synthetase XF2443 [imported] - Xylella; E=6e-16 pir:G75156; hypothetical protein PAB0277 - Pyrococcus abyssi (strain; E=3e-13 gb:AAF87102.1; AF284573_1 (AF284573) Nit protein 2 [Mus musculus]; E=4e-12 COG: XF2443; COG0388 Predicted amidohydrolase; E=6e-17 PFAM: PF00795; Carbon-nitrogen hydrolase; E=1.2e-40.
  
     0.772
RB8574
Conserved hypothetical protein-putative peptidylarginine deiminase or related enzymes; Best DB hits: BLAST: pir:E75284; conserved hypothetical protein - Deinococcus radiodurans; E=1e-36 gb:AAK05795.1; AE006400_5 (AE006400) conserved hypothetical; E=1e-35 pir:T50502; hypothetical protein T22D6.110 - Arabidopsis thaliana; E=7e-34 COG: DR2359; COG2957 Peptidylarginine deiminase and related enzymes; E=1e-37; Belongs to the agmatine deiminase family.
 
  
 0.680
sthA
PMID: 9922271 best DB hits: BLAST: swissprot:P27306; STHA_ECOLI SOLUBLE PYRIDINE NUCLEOTIDE; E=1e-154 swissprot:Q9XBQ9; STHA_AZOVI SOLUBLE PYRIDINE NUCLEOTIDE; E=1e-149 swissprot:P50529; STHA_VIBCH SOLUBLE PYRIDINE NUCLEOTIDE; E=1e-146 COG: VC0151; COG1249 Dihydrolipoamide dehydrogenase/glutathione; E=1e-147 PFAM: PF00070; Pyridine nucleotide-disulphide; E=6.5e-63 PF02852; Pyridine nucleotide-disulphide; E=1.6e-34.
     
 0.553
RB5716
Hypothetical protein; Best DB hits: BLAST: pir:T36788; hypothetical protein SCI30A.08 - Streptomyces; E=0.51 PFAM: PF02656; Domain of unknown function DUF; E=0.0074.
       0.552
guaA-2
GMP synthase; Catalyzes the synthesis of GMP from XMP.
   
 
 0.424
RB11975
Polyketide synthase; PMID: 10662695 PMID: 10649995 best DB hits: BLAST: gb:AAF26921.1; AF210843_18 (AF210843) polyketide synthase [Sorangium; E=0.0 gb:AAF26923.1; AF210843_20 (AF210843) polyketide synthase [Sorangium; E=0.0 gb:AAF62883.1; AF217189_6 (AF217189) epoD [Sorangium cellulosum]; E=0.0 COG: BS_fabD; COG0331 (acyl-carrier-protein) S-malonyltransferase; E=7e-31 PA2965; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase I; E=3e-28 PA5234; COG0604 NADPH:quinone reductase and related Zn-dependent; E=2e-27 PFAM: PF00108; Thiolase, N-terminal domain; E=7.3e-07 PF00109; Beta-ketoacyl s [...]
     
 0.402
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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