STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB5964Probable response regulatory protein; Best DB hits: BLAST: pir:H70302; conserved hypothetical protein aq_035 - Aquifex aeolicus; E=1e-28 pir:A71678; probable response regulatory protein RP237 - Rickettsia; E=3e-26 pir:E72220; conserved hypothetical protein - Thermotoga maritima; E=1e-24 COG: aq_035_2; COG2199 Diguanylate cyclase/phosphodiesterase domain 1; E=1e-29 TM1699_2; COG2206 HD-GYP domain; E=1e-24 aq_563_2; COG2199 Diguanylate cyclase/phosphodiesterase domain 1; E=2e-24 PFAM: PF01966; HD domain; E=6.6e-08 PF00989; PAS domain; E=0.032 PF00990; GGDEF domain; E=3.6e-53. (824 aa)    
Predicted Functional Partners:
RB12766
PMID: 11557134 best DB hits: BLAST: pir:C82181; conserved hypothetical protein VC1592 [imported] -; E=2e-15 pir:G70332; conserved hypothetical protein aq_367 - Aquifex aeolicus; E=6e-15 pir:D83238; hypothetical protein PA3258 [imported] - Pseudomonas; E=2e-13 COG: VC1592; COG2200 Diguanylate cyclase/phosphodiesterase domain 2 (EAL); E=1e-16 aq_367_3; COG2200 Diguanylate cyclase/phosphodiesterase domain 2; E=6e-16 VC1641; COG2200 Diguanylate cyclase/phosphodiesterase domain 2 (EAL); E=2e-09 PFAM: PF00498; FHA domain; E=6.6e-15 PF00563; Domain of unknown function 2; E=3.1e-07.
 
  
 0.907
RB3251
Conserved hypothetical protein; PMID: 8905231 best DB hits: BLAST: pir:S76102; hypothetical protein slr0359 - Synechocystis sp. (strain; E=3e-99 pir:S76238; hypothetical protein sll0267 - Synechocystis sp. (strain; E=2e-89 pir:S77565; hypothetical protein slr2077 - Synechocystis sp. (strain; E=5e-88 COG: PA0575_4; COG2200 Diguanylate cyclase/phosphodiesterase domain 2; E=1e-59 PFAM: PF00900; Ribosomal family S4e; E=0.72 PF00072; Response regulator receiver dom; E=3.8e-29 PF00785; PAC motif; E=0.054.
 
 
0.868
RB10488
PMID: 20572072 best DB hits: BLAST: pir:S75136; sensory transduction histidine kinase slr2104 -; E=3e-67 pir:E83443; probable sensorresponse regulator hybrid PA1611; E=2e-64 pir:H82211; sensory box sensor histidine kinaseresponse regulator; E=8e-61 COG: VC1349_2; COG0642 Sensory transduction histidine kinases; E=7e-62 PFAM: PF00785; PAC motif; E=0.00076 PF00512; His Kinase A (phosphoacceptor) d; E=1.6e-28 PF02518; Histidine kinase-, DNA gyrase B-; E=1.6e-42.
 
 
 0.825
RB159
PMID: 11406410 best DB hits: BLAST: pir:S75136; sensory transduction histidine kinase slr2104 -; E=2e-69 pir:S75130; sensory transduction histidine kinase slr2098 -; E=4e-63 pir:E83443; probable sensorresponse regulator hybrid PA1611; E=8e-62 COG: VC1349_2; COG0642 Sensory transduction histidine kinases; E=2e-53 PFAM: PF00989; PAS domain; E=5.9e-05 PF00512; His Kinase A (phosphoacceptor); E=4.2e-24 PF02518; Histidine kinase-, DNA gyrase B; E=4.1e-43.
 
  
 0.813
RB3373
PMID: 9098081 best DB hits: BLAST: pir:T28655; receptor-like histidine kinase BpdS - Rhodococcus sp; E=1e-60 pir:T30898; receptor-like histidine kinase - Rhodococcus erythropolis; E=1e-60 pir:S75136; sensory transduction histidine kinase slr2104 -; E=9e-58 COG: VC1349_2; COG0642 Sensory transduction histidine kinases; E=1e-41 PFAM: PF00069; Protein kinase domain; E=8.1e-08 PF00515; TPR Domain; E=0.026 PF00512; His Kinase A (phosphoacceptor); E=1.4e-21.
 
  
 0.808
RB10330
Best DB hits: BLAST: pir:S75136; sensory transduction histidine kinase slr2104 -; E=3e-69 pir:E83443; probable sensorresponse regulator hybrid PA1611; E=2e-56 pir:H83132; probable sensorresponse regulator hybrid PA4112; E=1e-52 COG: PA4982; COG0642 Sensory transduction histidine kinases; E=4e-49 PFAM: PF00512; His Kinase A (phosphoacceptor) d; E=1.3e-22 PF02518; Histidine kinase-, DNA gyrase B-; E=8e-46 PF00072; Response regulator receiver doma; E=6.2e-33.
 
  
 0.807
flgE
Flagellar hook protein FlgE; PMID: 10368149 best DB hits: BLAST: gb:AAD24206.1; AF049342_4 (AF049342) flagellar hook protein FlgE; E=8e-22 gb:AAA61738.1; (U19712) flagellar hook polypeptide [Borrelia; E=1e-21 gb:AAA91361.1; (U12870) flagellar distal rod protein [Borrelia; E=3e-21 COG: BB0283; COG1749 Flagellar basal body and hook proteins; E=5e-22 PFAM: PF00460; Flagella basal body rod protein; E=3.7e-10.
 
   0.806
RB10924
Probable sensor/response regulator hybrid; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
  
 
 0.792
RB4511
Sensory transduction histidine kinase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
  
 
 0.792
RB10065
Conserved hypothetical protein-putative phosphohydrolase involved in signal transduction; Best DB hits: BLAST: ddbj:BAA82692.1; (AB013492) ORF14 [Bacillus halodurans] -----; E=4e-20 pir:D83132; hypothetical protein PA4108 [imported] - Pseudomonas; E=4e-17 pir:E71268; conserved hypothetical protein TP0912 - syphilis; E=4e-15 COG: BH0008; COG2206 HD-GYP domain; E=4e-21.
  
 
 0.731
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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