STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB6199Dehydrogenase homolog; PMID: 8821935 best DB hits: BLAST: pir:S70672; dehydrogenase homolog - Bordetella pertussis -----; E=5e-50 gb:AAD45293.1; AF156256_1 (AF156256) putative dehydrogenase; E=3e-44 embl:CAC24056.1; (AL512981) Hypothetical-conserved [Sulfolobus; E=3e-43 COG: TM0585; COG0673 Predicted dehydrogenases and related proteins; E=2e-40 PFAM: PF01958; Domain of unknown function DUF; E=0.00025 PF01408; Oxidoreductase family, NAD-bin; E=2.1e-40 PF02894; Oxidoreductase family, C-termi; E=1.4e-16. (378 aa)    
Predicted Functional Partners:
RB2515
Probable UDP-glucose/GDP-mannose dehydrogenase; PMID: 10984043 best DB hits: BLAST: pir:A83252; probable UDP-glucoseGDP-mannose dehydrogenase WbpA; E=1e-124 pir:H72358; lipopolysaccharide biosynthesis protein - Thermotoga; E=4e-93 pir:F71153; probable Vi polysaccharide biosynthesis protein -; E=8e-85 COG: PA3159; COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; E=1e-125 VNG0046G; COG1004 Predicted UDP-glucose 6-dehydrogenase; E=9e-24 PFAM: PF00984; UDP-glucose/GDP-mannose dehydro; E=3.9e-131.
 
 
 0.944
degT
Pleiotropic regulatory protein; PMID: 2104607 best DB hits: BLAST: swissprot:P15263; DEGT_BACST PLEIOTROPIC REGULATORY PROTEIN; E=2e-80 ddbj:BAA31964.1; (D64132) A porR mutant of Pophyromonas; E=3e-68 pir:D69025; pleiotropic regulatory protein DegT - Methanobacterium; E=2e-67 COG: MTH1188; COG0399 Predicted pyridoxal phosphate-dependent enzyme; E=2e-68 PFAM: PF01041; DegT/DnrJ/EryC1/StrS family; E=1.2e-146; Belongs to the DegT/DnrJ/EryC1 family.
 
    0.720
RB5290
Probable NADH-dependent dehydrogenase; Best DB hits: BLAST: pir:T34927; probable oxidoreductase - Streptomyces coelicolor; E=2e-07 gb:AAC23913.1; (AF039207) NADH-dependent dehydrogenase homolog; E=6e-07 pir:B72359; lipopolysaccharide biosynthesis protein BplA -; E=3e-05 COG: TM0585; COG0673 Predicted dehydrogenases and related proteins; E=3e-06 PFAM: PF01408; Oxidoreductase family, NAD-bindi; E=3.2e-18.
  
     0.662
RB4631
Probable aminotransferase; Best DB hits: BLAST: gb:AAC38670.2; (AF062345) putative perosamine synthetase; LpsC; E=9e-10 gb:AAB81626.1; (AF025396) probable perosamine synthetase [Vibrio; E=1e-08 gb:AAD28492.1; AF145039_4 (AF145039) aminotransferase spcS2; E=5e-08 COG: PAB0774; COG0399 Predicted pyridoxal phosphate-dependent enzyme; E=1e-08 PFAM: PF01041; DegT/DnrJ/EryC1/StrS family; E=0.099; Belongs to the DegT/DnrJ/EryC1 family.
  
    0.659
RB3070
Conserved hypothetical protein-putative oxidoreductase; PMID: 10484179 best DB hits: BLAST: ddbj:BAB05884.1; (AP001514) BH2165~unknown conserved protein; E=1e-09 embl:CAC24034.1; (AL512980) ORF-c34_017 [Sulfolobus solfataricus]; E=4e-09 ddbj:BAB04967.1; (AP001511) NADH-dependent dyhydrogenase; E=1e-08 COG: BH2165; COG0673 Predicted dehydrogenases and related proteins; E=1e-10 PFAM: PF01408; Oxidoreductase family, NAD-bindi; E=1.3e-20.
  
     0.656
RB5365
Probable NADH-dependent dehydrogenase; Best DB hits: BLAST: gb:AAC23913.1; (AF039207) NADH-dependent dehydrogenase homolog; E=4e-10 gb:AAC31181.1; (AF076240) unknown [Rhizobium leguminosarum bv; E=2e-09 ddbj:BAB05884.1; (AP001514) BH2165~unknown conserved protein; E=6e-09 COG: BH2165; COG0673 Predicted dehydrogenases and related proteins; E=5e-10 PFAM: PF01408; Oxidoreductase family, NAD-bin; E=3.1e-15.
  
     0.629
mfd
Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
       0.572
RB8799
Probable NADH-dependent dyhydrogenase; Best DB hits: BLAST: ddbj:BAB04967.1; (AP001511) NADH-dependent dyhydrogenase; E=6e-11 ddbj:BAB05884.1; (AP001514) BH2165~unknown conserved protein; E=7e-11 pir:T34927; probable oxidoreductase - Streptomyces coelicolor; E=8e-11 COG: BH1248; COG0673 Predicted dehydrogenases and related proteins; E=6e-12 PFAM: PF01408; Oxidoreductase family, NAD-bin; E=9.9e-20.
  
     0.562
RB6207
Conserved hypothetical protein; PMID: 9389475 best DB hits: BLAST: gb:AAB89850.1; (AE001008) conserved hypothetical protein; E=2e-05 swissprot:P54741; AFSK_STRCO SERINETHREONINE PROTEIN KINASE AFSK; E=0.064 embl:CAB88430.1; (AL353815) serinethreonine protein kinase; E=0.064 COG: AF1399; COG1520 Uncharacterized proteins of WD40-like repeat family; E=2e-06 PFAM: PF01011; PQQ enzyme repeat; E=0.47 PF02316; Mu DNA-binding domain; E=0.84.
       0.537
RB6209
Conserved hypothetical protein; PMID: 8688087 best DB hits: BLAST: swissprot:Q58250; Y840_METJA HYPOTHETICAL PROTEIN MJ0840 -----; E=3e-29 pir:C69211; conserved hypothetical protein MTH834 - Methanobacterium; E=1e-24 gb:AAB90759.1; (AE001071) conserved hypothetical protein; E=8e-24 COG: MJ0840; COG1548 Predicted nucleotide-binding enzyme; E=2e-30 PFAM: PF00370; FGGY family of carbohydrate kinases,; E=0.78 PF01897; Protein of unknown function DUF66; E=8.5e-35.
       0.537
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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