STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB6227Best DB hits: BLAST: pir:T37039; hypothetical protein SCJ12.22 - Streptomyces coelicolor; E=6e-05 swissprot:P39066; ACUB_BACSU ACETOIN UTILIZATION ACUB PROTEIN; E=0.016 pir:T36952; conserved hypothetical protein SCJ1.19c - Streptomyces; E=0.021 COG: BS_acuB; COG0517 CBS domains; E=0.002 PFAM: PF00999; Sodium/hydrogen exchanger fami; E=0.024 PF00571; CBS domain; E=0.00084. (587 aa)    
Predicted Functional Partners:
guaA-2
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.887
RB6226
PMID: 10984043 best DB hits: BLAST: pir:D83026; conserved hypothetical protein PA4950 [imported] -; E=4e-52 swissprot:P39288; YJES_ECOLI HYPOTHETICAL 43.1 KD PROTEIN IN; E=1e-48 gb:AAG59362.1; AE005650_1 (AE005650) orf, hypothetical protein; E=2e-48 COG: PA4950; COG1600 Uncharacterized Fe-S protein; E=4e-53 PFAM: PF00037; 4Fe-4S binding domain; E=0.026.
  
    0.776
RB6225
Hypothetical protein.
       0.658
RB11991
Conserved hypothetical protein-putative histone deacetylase; PMID: 10567266 PMID: 7678591 PMID: 7934817 best DB hits: BLAST: swissprot:P28606; YGLA_SYNP2 HYPOTHETICAL 34.1 KD PROTEIN IN GLNA; E=5e-60 embl:CAA78368.1; (Z13965) Portion of hypothetical protein; E=5e-60 embl:CAA78369.1; (Z13965) Portion of hypothetical protein; E=2e-54 COG: DR0833; COG0123 Deacetylases, including yeast histone deacetylase; E=3e-51 PFAM: PF00850; Histone deacetylase family; E=1.2e-50.
  
  
 0.557
RB6221
Hypothetical protein-signal peptide and transmembrane prediction; PMID: 11759840.
       0.499
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.463
RB6236
Putative ABC transporter ATP-binding protein; PMID: 8590279 best DB hits: BLAST: swissprot:P22040; Y415_SYNY3 HYPOTHETICAL ABC TRANSPORTER; E=8e-56 gb:AAC36155.1; (AF003632) PilH [Myxococcus xanthus]; E=1e-48 pir:A39025; probable membrane protein, cpn60 5'-region -; E=7e-47 COG: sll0415; COG1131 ABC-type multidrug transport system, ATPase; E=7e-57 PFAM: PF00005; ABC transporter; E=1.4e-59.
  
    0.463
RB6230
Similar to IRE (iron responsive element); Best DB hits: BLAST: ddbj:BAA89783.1; (AB037133) IRE [Arabidopsis thaliana] -----; E=0.25.
       0.461
RB6233
Hypothetical protein.
       0.458
RB9823
Conserved hypothetical protein; Best DB hits: BLAST: swissprot:O67500; YF46_AQUAE HYPOTHETICAL PROTEIN AQ_1546 -----; E=3e-47 swissprot:P45313; YRBH_HAEIN HYPOTHETICAL PROTEIN HI1678 -----; E=2e-46 gb:AAK02609.1; (AE006087) KpsF [Pasteurella multocida]; E=3e-43 COG: aq_1546_1; COG0794 Predicted sugar phosphate isomerase involved in; E=7e-37 APE1838; COG0517 CBS domains; E=2e-08 PFAM: PF01380; SIS domain; E=1.1e-28 PF00571; CBS domain; E=0.059.
     
 0.450
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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