STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
manCPMID: 10567266 best DB hits: BLAST: pir:B75596; mannose-1-phosphate guanylyltransferase - Deinococcus; E=5e-67 pir:S75700; GDP-mannose pyrophosphorylase - Synechocystis sp; E=9e-59 ddbj:BAB03201.1; (AB046360) putative GOP-mannose phosphorylase; E=2e-52 COG: DRA0032; COG0836 Mannose-1-phosphate guanylyltransferase; E=5e-68 PFAM: PF01128; Uncharacterized protein famil; E=0.27 PF00483; Nucleotidyl transferase; E=1.8e-54 PF01050; Mannose-6-phosphate isomerase; E=3.3e-05. (356 aa)    
Predicted Functional Partners:
RB9832
Phosphomannomutase (pmm); Best DB hits: BLAST: pir:E71082; probable phospho-sugar mutase 2 - Pyrococcus horikoshii; E=1e-60 pir:H75104; phosphomannomutase (pmm) PAB0819 - Pyrococcus abyssi; E=7e-58 gb:AAB90779.1; (AE001073) phosphomannomutase (pmm) [Archaeoglobus; E=5e-53 COG: PH0923; COG1109 Phosphomannomutase; E=1e-61 PFAM: PF02878; Phosphoglucomutase/phosphomannomu; E=4.1e-29 PF02879; Phosphoglucomutase/phosphomannomu; E=1.2e-15 PF02880; Phosphoglucomutase/phosphomannomu; E=0.00028.
 
 
 0.945
amsG
UDP-galactose-lipid carrier transferase; PMID: 7596293 best DB hits: BLAST: swissprot:Q57491; Y872_HAEIN HYPOTHETICAL SUGAR TRANSFERASE HI0872; E=3e-56 swissprot:Q46628; AMSG_ERWAM UDP-GALACTOSE-LIPID CARRIER; E=5e-56 pir:S61891; undecaprenyl-phosphate galactosephosphotransferase (EC; E=5e-56 COG: HI0872; COG2148 Sugar transferases involved in lipopolysaccharide; E=2e-57 PFAM: PF00895; ATP synthase protein 8; E=0.37 PF02397; Bacterial sugar transferase; E=3.6e-89.
 
  
 0.934
gmd
GDP-D-mannose dehydratase 1; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.
  
 
 0.926
gmd-2
GDP-mannose 4,6 dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.
  
 
 0.926
pmm
Phosphomannomutase; PMID: 8083177 best DB hits: BLAST: gb:AAD56627.1; AF165218_2 (AF165218) Pgm [Streptococcus; E=2e-83 ddbj:BAB04825.1; (AP001510) phosphomannomutase [Bacillus; E=5e-79 swissprot:P18159; YHXB_BACSU PROBABLE PHOSPHOMANNOMUTASE (PMM); E=1e-77 COG: BH1106; COG1109 Phosphomannomutase; E=5e-80 VC2095; COG0033 Phosphoglucomutase; E=3e-11 PH0923; COG1109 Phosphomannomutase; E=5e-11 PFAM: PF02878; Phosphoglucomutase/phosphomannomu; E=1.6e-13 PF02880; Phosphoglucomutase/phosphomannomu; E=0.023 PF00408; Phosphoglucomutase/phosphomannomu; E=0.76.
 
 
 0.689
pmi
PMID: 8293960 best DB hits: BLAST: pir:B75598; probable mannose-6-phosphate isomerase - Deinococcus; E=7e-43 pir:H69848; mannose-6-phosphate isomerase homolog yjdE - Bacillus; E=5e-39 ddbj:BAA75351.1; (AB011838) mannnose-6 phospate isomelase; E=8e-39 COG: DRA0048; COG1482 Phosphomannose isomerase; E=7e-44 PFAM: PF01238; Phosphomannose isomerase type I; E=0.0026.
  
 0.676
RB6255
Best DB hits: BLAST: gb:AAD05534.1; (AF083240) deca-heme c-type cytochrome [Shewanella; E=4e-04 gb:AAD05531.1; (AF083240) c-type cytochrome precursor [Shewanella; E=4e-04 swissprot:P32707; NRFB_ECOLI CYTOCHROME C-TYPE PROTEIN NRFB; E=0.029 COG: MTH83; COG0457 TPR-repeat-containing proteins; E=0.007 PFAM: PF00515; TPR Domain; E=0.014.
       0.617
epsB
PMID: 7476194 best DB hits: BLAST: pir:G70066; capsular polysaccharide biosynthesis homolog ywqD -; E=2e-28 swissprot:Q45409; EPSB_BURSO EPS I POLYSACCHARIDE EXPORT PROTEIN; E=2e-28 pir:G82262; probable exopolysaccharide biosynthesis protein VC0937; E=8e-28 COG: BS_ywqD; COG0489 ATPases involved in chromosome partitioning; E=2e-29 VNG0946G; COG0455 ATPases involved in chromosome partitioning; E=3e-08 BH3027; COG2894 Septum formation inhibitor-activating ATPase; E=6e-08 PFAM: PF00142; 4Fe-4S iron sulfur cluster bindin; E=0.016 PF00991; ParA family ATPase; E=0.3.
 
  
 0.570
RB10401
Similar to type 8 capsule gene Cap8B; PMID: 8606192 PMID: 9045821 best DB hits: BLAST: gb:AAB49431.1; (U73374) Cap8B [Staphylococcus aureus]; E=6e-19 gb:AAC46085.1; (U81973) Cap5B [Staphylococcus aureus]; E=1e-18 ddbj:BAB07387.1; (AP001519) capsular polysaccharide biosynthesis; E=2e-18 COG: BH3668; COG0489 ATPases involved in chromosome partitioning; E=2e-19 MJ0547; COG0455 ATPases involved in chromosome partitioning; E=1e-04 PFAM: PF00142; 4Fe-4S iron sulfur cluster bindin; E=0.68.
 
  
 0.568
galE-3
UDP-glucose 4-epimerase; PMID: 11058132 best DB hits: BLAST: swissprot:Q9KDV3; GALE_BACHD UDP-GLUCOSE 4-EPIMERASE; E=9e-99 pir:A69184; UDP-glucose 4-epimerase - Methanobacterium; E=3e-98 gb:AAK06077.1; AE006428_1 (AE006428) UDP-glucose 4-epimerase (EC; E=2e-93 COG: BH1108; COG1087 UDP-glucose 4-epimerase; E=1e-100 TM0509; COG0451 Nucleoside-diphosphate-sugar epimerases; E=9e-41 MPN257; COG1087 UDP-glucose 4-epimerase; E=6e-38 PFAM: PF02716; Isoflavone reductase; E=0.13 PF02254; KTN NAD-binding domain; E=0.22 PF00984; UDP-glucose/GDP-mannose dehyd; E=0.0085.
     
 0.526
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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