STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hup-2Probable DNA-binding protein HU; PMID: 10910347 best DB hits: BLAST: pir:D82620; histone-like protein XF1943 [imported] - Xylella; E=4e-14 pir:JC6029; histone H1 homolog - Bordetella pertussis -----gb:; E=4e-13 ddbj:BAB05028.1; (AP001511) non-specific DNA-binding protein II; E=3e-05 COG: BH1309; COG0776 Bacterial nucleoid DNA-binding protein; E=3e-06 PFAM: PF00216; Bacterial DNA-binding protein; E=7.4e-07. (105 aa)    
Predicted Functional Partners:
rpsT
Probable 30S ribosomal protein S20; Binds directly to 16S ribosomal RNA.
  
  
 0.636
fabH-3
3-oxoacyl-(acyl-carrier protein) synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
   
   0.635
RB6274
Hypothetical protein.
       0.603
rpsO
Probable 30S ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
   
  
 0.570
rplS
50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
  
    0.546
RB6278
Probable cyclophilin type peptidylprolyl isomerase; PMID: 7584044 best DB hits: BLAST: ddbj:BAA07555.1; (D38552) The ha1539 protein is related to; E=1e-19 gb:AAF58019.1; (AE003807) CG7747 gene product [Drosophila; E=2e-18 pir:T48940; hypothetical protein F14L2.150 - Arabidopsis thaliana; E=4e-18 COG: VNG1914G; COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) -; E=3e-15 PFAM: PF00160; Cyclophilin type peptidyl-prol; E=6.4e-32.
  
    0.505
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.457
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.425
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.