STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hydGProbable hydrogenase regulatory protein HydG; PMID: 1756170 best DB hits: BLAST: gb:AAF33506.1; (AF170176) Salmonella typhimurium transcriptional; E=3e-12 gb:AAG59807.1; AF305914_2 (AF305914) HydG [Klebsiella oxytoca]; E=3e-12 swissprot:P25852; HYDG_SALTY TRANSCRIPTIONAL REGULATORY PROTEIN; E=4e-12 COG: hydG; COG2204 AAA superfamily ATPases with N-terminal receiver; E=2e-12 BS_yqiR_2; COG1221 NtrC family transcriptional regulators, ATPase; E=4e-08 glnG; COG2204 AAA superfamily ATPases with N-terminal receiver; E=1e-07 PFAM: PF00158; Sigma-54 interaction domain; E=2e-05. (500 aa)    
Predicted Functional Partners:
RB10924
Probable sensor/response regulator hybrid; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
  
 
 0.863
RB4511
Sensory transduction histidine kinase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
  
 
 0.863
flgE
Flagellar hook protein FlgE; PMID: 10368149 best DB hits: BLAST: gb:AAD24206.1; AF049342_4 (AF049342) flagellar hook protein FlgE; E=8e-22 gb:AAA61738.1; (U19712) flagellar hook polypeptide [Borrelia; E=1e-21 gb:AAA91361.1; (U12870) flagellar distal rod protein [Borrelia; E=3e-21 COG: BB0283; COG1749 Flagellar basal body and hook proteins; E=5e-22 PFAM: PF00460; Flagella basal body rod protein; E=3.7e-10.
  
  
 0.799
RB6369
Best DB hits: BLAST: gb:AAC69888.1; (AF098788) nuclear calmodulin-binding protein; E=0.13.
       0.773
RB6372
Hypothetical protein.
       0.773
trmE-2
Probable tRNA modification GTPase; PMID: 1552862 best DB hits: BLAST: swissprot:P25811; THDF_BACSU POSSIBLE THIOPHENE AND FURAN; E=7e-21 gb:AAK06340.1; AE006453_4 (AE006453) GTP-binding protein ThdF; E=3e-20 embl:CAA71458.1; (Y10436) orf452; translated orf similarity to; E=2e-17 COG: BS_thdF; COG0486 Predicted GTPase; E=7e-22 DR2308; COG1160 Predicted GTPases; E=8e-12 TP0550; COG0486 Predicted GTPase; E=1e-11 PFAM: PF00071; Ras family; E=0.77 PF02421; Ferrous iron transport protein B; E=1.3e-05 PF01926; GTPase of unknown function; E=1e-06; Belongs to the TRAFAC class TrmE-Era-EngA-EngB [...]
       0.773
RB6374
Best DB hits: BLAST: pir:T35587; hypothetical protein SC6G4.36c SC6G4.36c - Streptomyces; E=5e-11 pir:H70859; hypothetical protein Rv3037c - Mycobacterium; E=2e-10 COG: Rv3037c; COG0500 SAM-dependent methyltransferases; E=2e-11.
       0.773
RB4179
Ornithine decarboxylase inhibitor-putative sigma54 transciptional regulator; PMID: 8346225 best DB hits: BLAST: pir:A48291; ornithine decarboxylase inhibitor - Escherichia coli; E=4e-70 swissprot:Q06065; ATOC_ECOLI ACETOACETATE METABOLISM REGULATORY; E=4e-70 gb:AAG45333.1; AF273214_1 (AF273214) SasR [Myxococcus xanthus]; E=1e-69 COG: atoC; COG2204 AAA superfamily ATPases with N-terminal receiver; E=4e-71 aq_218_2; COG1221 NtrC family transcriptional regulators, ATPase; E=1e-63 TP0519; COG2204 AAA superfamily ATPases with N-terminal receiver; E=1e-63 PFAM: PF00498; FHA domain; E=6.7e-16 [...]
 
 
   0.765
atoC-3
Acetoacetate metabolism regulatory protein atoC; PMID: 9278503 PMID: 9097040 PMID: 8346225 best DB hits: BLAST: pir:F71315; probable response regulatory protein (atoC) - syphilis; E=1e-60 swissprot:P09570; NIFA_AZOVI NIF-SPECIFIC REGULATORY PROTEIN; E=2e-60 pir:A48291; ornithine decarboxylase inhibitor - Escherichia coli; E=3e-60 COG: TP0519; COG2204 AAA superfamily ATPases with N-terminal receiver; E=1e-61 aq_218_2; COG1221 NtrC family transcriptional regulators, ATPase; E=2e-59 hydG; COG2204 AAA superfamily ATPases with N-terminal receiver; E=9e-58 PFAM: PF00004; ATPase family associ [...]
  
 
   0.762
RB8745
PMID: 2722750 best DB hits: BLAST: swissprot:P12626; ANFA_AZOVI NITROGEN FIXATION PROTEIN ANFA; E=1e-64 pir:A48291; ornithine decarboxylase inhibitor - Escherichia coli; E=7e-61 swissprot:Q06065; ATOC_ECOLI ACETOACETATE METABOLISM REGULATORY; E=7e-61 COG: atoC; COG2204 AAA superfamily ATPases with N-terminal receiver; E=7e-62 ygeV_3; COG1221 NtrC family transcriptional regulators, ATPase; E=3e-61 TP0519; COG2204 AAA superfamily ATPases with N-terminal receiver; E=8e-60 PFAM: PF00498; FHA domain; E=1.4e-16 PF00158; Sigma-54 interaction domain; E=1.6e-129 PF02001; Protein of unknown func [...]
 
 
   0.760
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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