STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB6395Probable PKR inhibitor (translation regulation); PMID: 7511204 best DB hits: BLAST: pir:A56534; P58 protein - bovine ----- gb: AAA17795.1; E=2e-08 gb:AAC52592.1; (U28423) p58 [Mus musculus]; E=1e-07 gb:AAC50502.1; (U28424) p58 [Homo sapiens]; E=2e-07 COG: BB0210; COG0457 TPR-repeat-containing proteins; E=2e-04 PFAM: PF00515; TPR Domain; E=0.65. (778 aa)    
Predicted Functional Partners:
RB12056
Conserved hypothetical protein containing TPR domain; PMID: 10192388 best DB hits: BLAST: pir:T39943; hypothetical protein SPBC23E6.09 - fission yeast; E=2e-04 pir:C72048; tpr repeats-ct683 hypothetical protein - Chlamydophila; E=0.006 swissprot:P42810; YAG7_PSEAE HYPOTHETICAL PROTEIN PA4667 -----; E=0.24 COG: CPn0693; COG0457 TPR-repeat-containing proteins; E=6e-04 PFAM: PF00515; TPR Domain; E=0.0018 PF00903; Glyoxalase/Bleomycin resistance; E=0.85 PF00515; TPR Domain; E=0.52.
 
     0.687
RB7947
Probable O-linked GlcNAc transferase; PMID: 9083067 PMID: 97238870 best DB hits: BLAST: gb:AAF26789.1; AC016829_13 (AC016829) putative O-linked GlcNAc; E=2e-09 gb:AAA62535.1; (U21320) contains TPR domain-like repeats; E=2e-08 gb:AAB63465.1; (U77412) O-linked GlcNAc transferase; E=2e-08 COG: sll0886; COG0457 TPR-repeat-containing proteins; E=2e-07 PFAM: PF00515; TPR Domain; E=0.025.
  
     0.664
RB6398
Hypothetical protein.
       0.580
RB6403
Probable response regulator; PMID: 10910347 best DB hits: BLAST: pir:T34675; probable response regulator - Streptomyces coelicolor; E=1e-05 pir:A82535; transcription regulator LuxRUhpA family XF2608; E=4e-05 pir:T35105; probable two-component regulator - Streptomyces; E=7e-05 COG: XF2608; COG2197 Response regulators consisting of a CheY-like; E=4e-06 PA3420; COG2909 ATP-dependent transcriptional regulator; E=4e-04 PA3714; COG2197 Response regulators consisting of a CheY-like; E=4e-04 PFAM: PF00989; PAS domain; E=4.2e-06 PF00196; Bacterial regulatory proteins, luxR; E=3.1e-14.
   
 
 0.568
RB10541
Similar to O-linked GlcNAc transferase-putativeTPR repeat containing protein; Best DB hits: BLAST: gb:AAF26789.1; AC016829_13 (AC016829) putative O-linked GlcNAc; E=1e-05 swissprot:P56558; OGT1_RAT UDP-N-ACETYLGLUCOSAMINE--PEPTIDE; E=3e-05 gb:AAF31458.1; (AF223393) HRNT1 [Homo sapiens]; E=3e-05 COG: TP0468; COG0457 TPR-repeat-containing proteins; E=7e-04 PFAM: PF00515; TPR Domain; E=0.00012.
  
     0.564
RB8077
Hypothetical protein-signal peptide and transmembrane prediction.
  
     0.539
RB9329
Probable WD-repeat containing protein; Best DB hits: BLAST: embl:CAB45034.1; (AL078635) putative WD-repeat containing protein; E=1e-12 swissprot:Q00808; HET1_PODAN VEGETATIBLE INCOMPATIBILITY PROTEIN; E=5e-12 gb:AAG40737.1; AF299085_1 (AF299085) Bap1 [Myxococcus xanthus]; E=3e-09 COG: slr0143_2; COG2319 WD40 repeat protein; E=2e-09 PFAM: PF00400; WD domain, G-beta repeat; E=0.87.
  
 
  0.526
RB2761
Probable outer membrane protein A (OmpA); PMID: 1447140 PMID: 9742696 best DB hits: BLAST: gb:AAD40344.1; U88088_22 (U88088) OmpA [Pseudomonas alcaligenes]; E=5e-08 swissprot:Q10557; Y899_MYCTU HYPOTHETICAL 33.6 KDA PROTEIN RV0899; E=3e-07 gb:AAD39495.1; AF145799_1 (AF145799) immunogenic 23 kDa; E=1e-06 COG: Rv0899; COG2885 Outer membrane protein and related; E=2e-08 aq_1002; COG1360 Flagellar motor protein; E=2e-07 XF0363; COG2885 Outer membrane protein and related; E=1e-05 PFAM: PF01486; K-box region; E=0.5 PF00691; OmpA family; E=4.9e-06.
  
 
   0.499
RB6400
Hypothetical protein-transmembrane prediction; Best DB hits: PFAM: PF00397; WW domain; E=0.54.
       0.488
exoF
PMID: 8439670 best DB hits: BLAST: pir:F70345; polysaccharide biosynthesis protein - Aquifex aeolicus; E=2e-07 pir:S70958; otnA protein - Vibrio cholerae -----embl:; E=1e-06 swissprot:Q02728; EXOF_RHIME EXOPOLYSACCHARIDE PRODUCTION PROTEIN; E=3e-05 COG: aq_505; COG1596 Periplasmic protein involved in polysaccharide; E=2e-08 yccZ; COG1596 Periplasmic protein involved in polysaccharide export; E=1e-05 PA2234; COG1596 Periplasmic protein involved in polysaccharide; E=0.001 PFAM: PF00159; Pancreatic hormone peptide; E=0.82.
  
 
   0.487
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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