STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rarDPMID: 10952301 best DB hits: BLAST: pir:D82351; rarD protein VC0195 [imported] - Vibrio cholerae (group; E=4e-38 embl:CAC08293.1; (AL392148) putative integral membrane protein; E=1e-36 gb:AAG59015.1; AE005613_8 (AE005613) orf, hypothetical protein; E=1e-35 COG: VC0195; COG2962 Predicted permeases; E=3e-39 PFAM: PF00892; Integral membrane protein DUF6; E=5.7e-12. (314 aa)    
Predicted Functional Partners:
RB6500
Mycocerosate synthase; PMID: 3880746 best DB hits: BLAST: pir:S72705; mycocerosate synthase (EC 2.3.1.111) - Mycobacterium; E=0.0 pir:H70819; probable polyketide synthase - Mycobacterium tuberculosis; E=0.0 gb:AAF62883.1; AF217189_6 (AF217189) epoD [Sorangium cellulosum]; E=1e-180 COG: PA2402_3; COG1020 Non-ribosomal peptide synthetase modules and related; E=4e-99 BS_ppsD_3; COG1020 Non-ribosomal peptide synthetase modules and; E=4e-92 PA2424_2; COG1020 Non-ribosomal peptide synthetase modules and related; E=1e-91 PFAM: PF00108; Thiolase, N-terminal domain; E=2.7e-06 PF00109; Beta-keto [...]
       0.778
RB6498
Hypothetical protein.
       0.773
RB6502
PMID: 9371463 best DB hits: BLAST: pir:F69192; conserved hypothetical protein MTH695 - Methanobacterium; E=2e-30 swissprot:Q58902; YF07_METJA HYPOTHETICAL PROTEIN MJ1507 -----; E=5e-10 gb:AAB89778.1; (AE001001) conserved hypothetical protein; E=2e-09 COG: MTH695; COG0577 Predicted permease; E=2e-31 PFAM: PF02687; Predicted permease; E=4.3e-26.
       0.773
RB6504
Hypothetical protein.
       0.741
RB6505
Hypothetical protein.
       0.741
RB6506
Hypothetical protein.
       0.741
rnpA
Probable ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
   
  
 0.704
spoIIIE
Stage III sporulation protein E; PMID: 3129532 PMID: 2507870 PMID: 8160014 best DB hits: BLAST: swissprot:P21458; SP3E_BACSU STAGE III SPORULATION PROTEIN E; E=1e-108 pir:C69999; DNA translocase stage III sporulation homolog ytpT -; E=1e-106 swissprot:P45264; FTSK_HAEIN CELL DIVISION PROTEIN FTSK HOMOLOG; E=1e-105 COG: BS_spoIIIE; COG1674 DNA segregation ATPase FtsK/SpoIIIE and related; E=1e-109 ftsK; COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins; E=6e-97 CT739; COG1674 DNA segregation ATPase FtsK/SpoIIIE and related; E=6e-97 PFAM: PF01580; FtsK/SpoIIIE family; E=9.7e-66.
      
 0.602
korB
2-oxoglutarate ferredoxin oxidoreductase beta subunit; PMID: 11401501 best DB hits: BLAST: embl:CAC08295.1; (AL392148) putative oxidoreductase [Streptomyces; E=1e-104 embl:CAB60188.1; (AL132824) putative oxidoreductase beta-subunit; E=1e-103 pir:E70864; probable oxidoreductase - Mycobacterium tuberculosis; E=2e-94 COG: Rv2454c; COG1013 Pyruvate:ferredoxin oxidoreductase and related; E=1e-95 PFAM: PF02775; Thiamine pyrophosphate enzyme,; E=0.19.
      0.580
yidC
60 kDa inner-membrane protein homolog-putative part of a protein secretion system; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins (By similarity).
      
 0.553
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.