STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prfBPeptide chain release factor 2 (RF-2); Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. (337 aa)    
Predicted Functional Partners:
rplU
50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
   
   0.962
rplM
50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
   0.953
rpsP
Probable 30S ribosomal protein S16; PMID: 6357787 PMID: 8730873 best DB hits: BLAST: pir:T05282; ribosomal protein S16, organellar - Arabidopsis; E=3e-15 gb:AAK05667.1; AE006387_10 (AE006387) 30S ribosomal protein S16; E=7e-14 ddbj:BAA97024.1; (AB024035) 30S ribosomal protein S16; E=1e-13 COG: BH2483; COG0228 Ribosomal protein S16; E=2e-14 PFAM: PF00886; Ribosomal protein S16; E=1.8e-20; Belongs to the bacterial ribosomal protein bS16 family.
 
 
 0.951
rpsG
30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
  
 
 0.943
rpmA
50S ribosomal protein L27; PMID: 10617197 PMID: 1225626 best DB hits: BLAST: gb:AAC64229.1; (AC005167) 50S ribosomal protein L27 [Arabidopsis; E=4e-19 swissprot:O87885; RL27_LAWIN 50S RIBOSOMAL PROTEIN L27 -----; E=1e-18 pir:T49957; ribosomal protein L27-like - Arabidopsis thaliana; E=2e-18 COG: VC0436; COG0211 Ribosomal protein L27; E=2e-18 PFAM: PF01016; Ribosomal L27 protein; E=6.4e-44; Belongs to the bacterial ribosomal protein bL27 family.
   
 
 0.941
rplT
Probable 50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
  
 
 0.939
rpsL
30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy.
  
 
 0.938
rplD
50S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
  
 
 0.918
rplA
50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
  
 
 0.914
rplS
50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
 
 
 0.910
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.