STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB686Arylsulfatase; PMID: 7744061 best DB hits: BLAST: swissprot:P51691; ARS_PSEAE ARYLSULFATASE (ARYL-SULFATE; E=4e-51 pir:S69336; arylsulfatase (EC 3.1.6.1) - Pseudomonas aeruginosa; E=8e-51 gb:AAF71377.1; AF262990_2 (AF262990) arylsulfatase [Klebsiella; E=1e-41 COG: PA0183; COG3119 Arylsulfatase A and related enzymes; E=4e-52 PFAM: PF00884; Sulfatase; E=2.2e-86. (549 aa)    
Predicted Functional Partners:
RB7746
Probable sulfatase atsD; Best DB hits: BLAST: pir:B70535; probable sulfatase (EC 3.1.6.-) atsD - Mycobacterium; E=7e-11 pir:E70533; probable sulfatase (EC 3.1.6.-) atsB - Mycobacterium; E=4e-08 pir:B70643; probable sulfatase (EC 3.1.6.-) atsA - Mycobacterium; E=0.22 COG: Rv0663; COG3119 Arylsulfatase A and related enzymes; E=7e-12.
 
     0.830
RB684
Arylsulfatase; PMID: 7744061 best DB hits: BLAST: swissprot:P51691; ARS_PSEAE ARYLSULFATASE (ARYL-SULFATE; E=3e-67 pir:S69336; arylsulfatase (EC 3.1.6.1) - Pseudomonas aeruginosa; E=3e-66 gb:AAF71377.1; AF262990_2 (AF262990) arylsulfatase [Klebsiella; E=1e-53 COG: PA0183; COG3119 Arylsulfatase A and related enzymes; E=3e-68 HI1246; COG1368 Phosphoglycerol transferase and related proteins,; E=2e-05 PA2333; COG3119 Arylsulfatase A and related enzymes; E=4e-04 PFAM: PF00884; Sulfatase; E=1.3e-78.
 
    
0.822
RB693
Conserved hypothetical protein; PMID: 7542800 PMID: 11997336 best DB hits: BLAST: swissprot:P43965; YAFM_HAEIN HYPOTHETICAL PROTEIN HI0217 -----; E=0.012 COG: HI0217; COG1943 Predicted transposase; E=0.001.
 
     0.803
RB691
Hypothetical protein.
       0.773
RB695
N-acetyl-galactosamine-6-sulfatase (GALNS); PMID: 20164110 best DB hits: BLAST: ddbj:BAA04535.1; (D17629) N-acetylgalactosamine 6-sulfate; E=2e-39 gb:AAF63858.1; (AF112242) N-acetylgalactosamine-6-sulfate; E=3e-38 gb:AAF49287.1; (AE003522) CG7402 gene product [Drosophila; E=3e-31 COG: PA0183; COG3119 Arylsulfatase A and related enzymes; E=3e-30 VCA0802; COG1368 Phosphoglycerol transferase and related proteins,; E=1e-04 VNG0061C; COG3119 Arylsulfatase A and related enzymes; E=2e-04 PFAM: PF00143; Interferon alpha/beta domain; E=0.59 PF00884; Sulfatase; E=1.9e-42.
 
    
0.708
RB683
Aldehyde dehydrogenase; PMID: 7484410 best DB hits: BLAST: gb:AAF52769.1; (AE003624) CG3752 gene product [Drosophila; E=5e-73 ddbj:BAA34785.1; (AB015226) RALDH2 [Homo sapiens]; E=2e-72 swissprot:O94788; DHAS_HUMAN RETINALDEHYDE-SPECIFIC DEHYDROGENASE; E=2e-72 COG: YOR374w; COG1012 NAD-dependent aldehyde dehydrogenases; E=2e-71 PFAM: PF00171; Aldehyde dehydrogenase family; E=7e-156.
  
    0.576
fucA-2
PMID: 2664711 best DB hits: BLAST: pir:E72546; L-fuculose-phosphate aldolase homolog - Aeropyrum pernix; E=6e-15 pir:C69054; L-fuculose-phosphate aldolase homolog - Methanobacterium; E=3e-14 swissprot:Q57199; YGBL_HAEIN HYPOTHETICAL PROTEIN HI1012 -----; E=9e-13 COG: APE1657; COG0235 Ribulose-5-phosphate 4-epimerase and related; E=6e-16 PFAM: PF00596; Class II Aldolase and Adducin N-t; E=8.8e-19.
       0.473
ramA
alfa-L-rhamnosidase; PMID: 10632887 best DB hits: BLAST: embl:CAB53341.1; (AJ238748) alfa-L-rhamnosidase [Clostridium; E=1e-103 pir:T36406; hypothetical protein SCF34.07 - Streptomyces coelicolor; E=4e-89 embl:CAB55731.1; (AL117387) putative secreted protein [Streptomyces; E=1e-69 PFAM: PF02083; Urotensin II; E=0.87.
       0.429
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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