STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lolCProbable lipoprotein releasing system transmembrane protein LolC; PMID: 10783239 best DB hits: BLAST: pir:E71676; hypothetical protein RP699 - Rickettsia prowazekii; E=2e-19 pir:C83271; conserved hypothetical protein PA2986 [imported] -; E=1e-17 pir:E83271; conserved hypothetical protein PA2988 [imported] -; E=4e-16 COG: RP699; COG0577 Predicted permease; E=2e-20 PFAM: PF02687; Predicted permease; E=3.5e-39. (532 aa)    
Predicted Functional Partners:
lolD-2
Lipoprotein releasing system ATP-binding protein LolD; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
 
 0.992
lolD
Lipoprotein releasing system ATP-binding protein lolD; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
  
 0.980
macB
ABC transporter, ATP-binding protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
 
0.743
RB149
Probable outer membrane channel protein; PMID: 9852029 best DB hits: BLAST: gb:AAD12177.1; (AF029405) outer membrane channel protein; E=0.001 gb:AAD30205.1; (AF094824) IbeB [Escherichia coli]; E=0.039 swissprot:Q51487; OPRM_PSEAE OUTER MEMBRANE PROTEIN OPRM PRECURSOR; E=0.049 COG: PA0427; COG1538 Outer membrane protein; E=0.005 PFAM: PF02321; Outer membrane efflux protein; E=0.0013.
      
 0.680
RB4866
PMID: 10783239 best DB hits: BLAST: swissprot:P75957; LOLD_ECOLI LIPOPROTEIN RELEASING SYSTEM; E=6e-38 ddbj:BAA35937.1; (D90747) Heterocyst maturation protein (devA); E=6e-38 swissprot:O53899; Y986_MYCTU HYPOTHETICAL ABC TRANSPORTER; E=4e-37 COG: Rv0986; COG1136 ABC-type (unclassified) transport system, ATPase; E=4e-38 PA5503; COG1135 Uncharacterized ABC-type transport system ATPase; E=6e-33 PA4594; COG1136 ABC-type (unclassified) transport system, ATPase; E=8e-33 PFAM: PF00005; ABC transporter; E=9.9e-55.
  
   0.658
RB6469
Best DB hits: BLAST: pir:F82572; sodium ABC transporter ATP-binding protein XF2329; E=8e-44 swissprot:P46903; NATA_BACSU ATP-BINDING TRANSPORT PROTEIN NATA; E=2e-40 pir:B75459; sodium extrusion protein NatA - Deinococcus radiodurans; E=3e-39 COG: XF2329; COG1131 ABC-type multidrug transport system, ATPase; E=8e-45 ybhF; COG1131 ABC-type multidrug transport system, ATPase component; E=7e-32 PFAM: PF00448; SRP54-type protein, GTPase do; E=0.26 PF00005; ABC transporter; E=6.2e-51.
  
  
 0.651
RB6982
ABC transporter, ATP-binding protein; PMID: 10952301 best DB hits: BLAST: swissprot:Q9WYI7; Y352_THEMA HYPOTHETICAL ABC TRANSPORTER; E=4e-61 pir:A82184; ABC transporter, ATP-binding protein VC1568 [imported] -; E=4e-59 ddbj:BAB07392.1; (AP001519) ABC transporter (ATP-binding protein); E=2e-57 COG: TM0352; COG1136 ABC-type (unclassified) transport system, ATPase; E=4e-62 PFAM: PF00485; Phosphoribulokinase / Uridine; E=0.53 PF00005; ABC transporter; E=3.1e-55.
  
   0.650
RB10473
Best DB hits: BLAST: pir:D71687; alkaline proteinase secretion protein apre (aprE) RP314; E=0.032 pir:E82263; conserved hypothetical protein VC0913 [imported] -; E=0.053 gb:AAK03081.1; (AE006139) unknown [Pasteurella multocida]; E=0.13 COG: RP314; COG0845 Membrane-fusion protein; E=0.003 PFAM: PF01590; GAF domain; E=0.00029 PF00364; Biotin-requiring enzyme; E=0.0022.
  
 
   0.614
RB3729
ATP-binding subunit of ABC transporter; PMID: 9767151 best DB hits: BLAST: pir:A55541; heterocyst maturation protein devA - Anabaena sp; E=4e-54 embl:CAA05977.1; (AJ003195) ATP-binding subunit [Anabaena; E=1e-53 pir:S76632; hypothetical protein - Synechocystis sp. (strain PCC; E=2e-49 COG: sll0484; COG1136 ABC-type (unclassified) transport system, ATPase; E=2e-50 PA2350; COG1135 Uncharacterized ABC-type transport system ATPase; E=6e-26 TM0352; COG1136 ABC-type (unclassified) transport system, ATPase; E=2e-25 PFAM: PF01583; Adenylylsulfate kinase; E=0.19 PF00005; ABC transporter; E=3.2e [...]
 
 
 0.613
RB7232
Best DB hits: BLAST: pir:G69192; ABC transporter (glutamine transport ATP-binding; E=5e-39 pir:A82184; ABC transporter, ATP-binding protein VC1568 [imported] -; E=5e-38 pir:H72342; ABC transporter, ATP-binding protein - Thermotoga; E=6e-38 COG: MTH696; COG1136 ABC-type (unclassified) transport system, ATPase; E=5e-40 PFAM: PF00005; ABC transporter; E=6.5e-58.
  
   0.601
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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