STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB7019Best DB hits: BLAST: pir:H70988; hypothetical protein Rv1767 - Mycobacterium; E=0.065 pir:C69225; conserved hypothetical protein MTH935 -; E=0.14 COG: Rv1767; COG0599 Uncharacterized ACR, homolog of; E=0.006 PFAM: PF02627; Carboxymuconolactone decarboxylase; E=1e-08. (129 aa)    
Predicted Functional Partners:
hemD
PMID: 7665501 best DB hits: BLAST: gb:AAK00606.1; AF221100_3 (AF221100) uroporphyrinogen III; E=1e-89 swissprot:Q59294; HEM4_CLOJO PORPHYRIN BIOSYNTHESIS PROTEIN HEMD; E=1e-64 gb:AAC18588.1; (AF064061) uroporphyrinogen-III; E=3e-63 COG: NMB1156_2; COG0007 Uroporphyrinogen-III methylase; E=2e-44 sll0166_2; COG1587 Uroporphyrinogen-III synthase; E=7e-30 PFAM: PF00590; Tetrapyrrole (Corrin/Porphyrin); E=1.2e-63 PF02602; Uroporphyrinogen-III synthase H; E=7.1e-43.
       0.791
mmsB
3-hydroxyisobutyrate dehydrogenase; PMID: 1339433 best DB hits: BLAST: swissprot:P44979; YGBJ_HAEIN HYPOTHETICAL PROTEIN HI1010 -----; E=3e-48 gb:AAK03450.1; (AE006174) unknown [Pasteurella multocida]; E=8e-47 gb:AAF25989.1; AC013354_8 (AC013354) F15H18.21 [Arabidopsis; E=6e-46 COG: HI1010; COG2084 3-hydroxyisobutyrate dehydrogenase and related; E=3e-49 PFAM: PF01089; Delta 1-pyrroline-5-carboxylate; E=0.035 PF02737; 3-hydroxyacyl-CoA dehydrogenase,; E=0.00065 PF02254; KTN NAD-binding domain; E=8.4e-05.
  
  
 0.584
RB3816
3-hydroxyisobutyrate dehydrogenase; PMID: 2647728 best DB hits: BLAST: pir:T08967; hypothetical protein F19B15.150 - Arabidopsis thaliana; E=3e-78 swissprot:O34948; YKWC_BACSU HYPOTHETICAL 30.7 KD PROTEIN IN; E=8e-71 gb:AAK06313.1; AE006450_6 (AE006450) 3-hydroxyisobutyrate; E=6e-70 COG: BS_ykwC; COG2084 3-hydroxyisobutyrate dehydrogenase and related; E=7e-72.
  
  
 0.584
purB
Adenylosuccinate lyase; PMID: 96015068 PMID: 2111814 best DB hits: BLAST: gb:AAB60684.1; (U20225) adenylosuccinate lyase [Mus musculus]; E=1e-144 gb:AAC83935.1; (AF106656) adenylosuccinate lyase [Homo sapiens]; E=1e-140 gb:AAH00253.1; AAH00253 (BC000253) adenylosuccinate lyase [Homo; E=1e-140 COG: YLR359w; COG0015 Adenylosuccinate lyase; E=1e-132 PFAM: PF00206; Lyase; E=2.5e-57; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
 
  
 0.557
rpsT
Probable 30S ribosomal protein S20; Binds directly to 16S ribosomal RNA.
       0.515
RB6500
Mycocerosate synthase; PMID: 3880746 best DB hits: BLAST: pir:S72705; mycocerosate synthase (EC 2.3.1.111) - Mycobacterium; E=0.0 pir:H70819; probable polyketide synthase - Mycobacterium tuberculosis; E=0.0 gb:AAF62883.1; AF217189_6 (AF217189) epoD [Sorangium cellulosum]; E=1e-180 COG: PA2402_3; COG1020 Non-ribosomal peptide synthetase modules and related; E=4e-99 BS_ppsD_3; COG1020 Non-ribosomal peptide synthetase modules and; E=4e-92 PA2424_2; COG1020 Non-ribosomal peptide synthetase modules and related; E=1e-91 PFAM: PF00108; Thiolase, N-terminal domain; E=2.7e-06 PF00109; Beta-keto [...]
  
  
 0.445
RB11975
Polyketide synthase; PMID: 10662695 PMID: 10649995 best DB hits: BLAST: gb:AAF26921.1; AF210843_18 (AF210843) polyketide synthase [Sorangium; E=0.0 gb:AAF26923.1; AF210843_20 (AF210843) polyketide synthase [Sorangium; E=0.0 gb:AAF62883.1; AF217189_6 (AF217189) epoD [Sorangium cellulosum]; E=0.0 COG: BS_fabD; COG0331 (acyl-carrier-protein) S-malonyltransferase; E=7e-31 PA2965; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase I; E=3e-28 PA5234; COG0604 NADPH:quinone reductase and related Zn-dependent; E=2e-27 PFAM: PF00108; Thiolase, N-terminal domain; E=7.3e-07 PF00109; Beta-ketoacyl s [...]
  
  
 0.440
pcxB
PMID: 8407791 best DB hits: BLAST: pir:E83626; protocatechuate 3,4-dioxygenase, beta subunit PA0153; E=1e-14 pir:T35018; protocatechuate 3,4-dioxygenase beta chain -; E=1e-14 gb:AAF65837.1; AF253466_3 (AF253466) protocatechuate; E=3e-14 PFAM: PF00652; QXW lectin repeat; E=0.28 PF00775; Dioxygenase; E=3.6e-18.
  
  
 0.418
prdX2
Peroxiredoxin 2; PMID: 9115640 best DB hits: BLAST: ref:XP_009063.1; TR00071480_p [Homo sapiens]; E=2e-62 swissprot:Q61171; PDX2_MOUSE PEROXIREDOXIN 2 (THIOREDOXIN; E=3e-62 swissprot:P32119; PDX2_HUMAN PEROXIREDOXIN 2 (THIOREDOXIN; E=4e-62 COG: PA0848; COG0450 Thiol - alkyl hydroperoxide reductases; E=4e-60 PFAM: PF00578; AhpC/TSA family; E=1e-71.
  
  
 0.406
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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