STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pheTphenylalanyl-tRNA synthetase beta chain; PMID: 2991205 best DB hits: BLAST: swissprot:P07395; SYFB_ECOLI PHENYLALANYL-TRNA SYNTHETASE BETA; E=3e-78 gb:AAG56700.1; AE005394_9 (AE005394) phenylalanine tRNA; E=6e-78 embl:CAA23565.1; (V00291) phenylalanyl-tRNA synthetase; E=3e-77 COG: pheT_2; COG0072 Phenylalanyl-tRNA synthetase beta subunit; E=3e-79 PFAM: PF01588; Putative tRNA binding domain; E=2.2e-05. (681 aa)    
Predicted Functional Partners:
pheS
phenylalanyl-tRNA synthetase alpha chain; PMID: 6317865 best DB hits: BLAST: embl:CAA23564.1; (V00291) phenylalanyl-tRNA synthetase; E=6e-76 gb:AAA51469.1; (K02844) phenylalanyl-tRNA synthetase; E=6e-76 swissprot:P08312; SYFA_ECOLI PHENYLALANYL-TRNA SYNTHETASE ALPHA; E=3e-75 COG: pheS; COG0016 Phenylalanyl-tRNA synthetase alpha subunit; E=3e-76 PFAM: PF02912; Aminoacyl tRNA synthetase class; E=3.9e-08 PF01409; tRNA synthetases class II (F); E=9.4e-92; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
 
 0.999
ileS
Probable isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
  
 
 0.909
lueS
Putative leucyl-tRNA synthetase; PMID: 1317842 best DB hits: BLAST: ddbj:BAB17162.1; (AP002868) putative leucyl-tRNA synthetase; E=0.0 embl:CAB77903.1; (AL161500) putative leucyl tRNA synthetase; E=0.0 gb:AAK04914.1; AE006315_3 (AE006315) leucyl-tRNA synthetase (EC; E=0.0 COG: TP0586; COG0495 Leucyl-tRNA synthetase; E=0.0 PFAM: PF00133; tRNA synthetases class I (I, L; E=1.4e-39; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
  
 0.908
guaA-2
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.855
argS
arginyl-tRNA synthetase; PMID: 2668891 best DB hits: BLAST: pir:G82121; arginyl-tRNA synthetase VC2074 [imported] - Vibrio; E=1e-69 swissprot:Q55486; SYR_SYNY3 ARGINYL-TRNA SYNTHETASE; E=5e-68 embl:CAC01600.1; (AJ269505) putative arginyl-tRNA synthetase; E=4e-66 COG: VC2074; COG0018 Arginyl-tRNA synthetase; E=1e-70 PFAM: PF00750; tRNA synthetases class I (R); E=5.7e-55.
  
  
 0.812
rspB
Ribosomal protein S2; PMID: 6806564 PMID: 6272196 PMID: 7023985 PMID: 10094780 best DB hits: BLAST: pir:F75386; ribosomal protein S2 - Deinococcus radiodurans (strain; E=9e-52 swissprot:Q9WZM1; RS2_THEMA 30S RIBOSOMAL PROTEIN S2 -----; E=2e-51 pdb:1FJF; B Chain B, Structure Of The Thermus Thermophilus 30s; E=2e-50 COG: DR1513; COG0052 Ribosomal protein S2; E=8e-53 PFAM: PF00318; Ribosomal protein S2; E=1.2e-82; Belongs to the universal ribosomal protein uS2 family.
   
 
 0.803
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
  
 0.788
rplO
50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
  
  
 0.781
rpoB
DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
  
 0.780
rpsC
30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
  
 
 0.758
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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