STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cstACarbon starvation-induced protein; PMID: 99411980 best DB hits: BLAST: ddbj:BAB05512.1; (AP001513) carbon starvation-induced protein; E=3e-82 swissprot:O67304; CSTA_AQUAE CARBON STARVATION PROTEIN A HOMOLOG; E=5e-65 pir:E75032; carbon starvation protein A homolog PAB1554 [similarity]; E=1e-53 COG: BH1793; COG1966 Carbon starvation protein, predicted membrane; E=3e-83 yjiY; COG1966 Carbon starvation protein, predicted membrane protein; E=2e-47 jhp1095; COG1966 Carbon starvation protein, predicted membrane; E=3e-47 PFAM: PF02554; Carbon starvation protein CstA; E=2.2e-104. (634 aa)    
Predicted Functional Partners:
putA
PMID: 96062224 best DB hits: BLAST: pir:H64526; proline dehydrogenase (EC 1.5.99.8); E=0.0 pir:B71980; proline dehydrogenase (EC 1.5.99.8); E=0.0 pir:C81297; proline dehydrogenase (EC 1.5.99.8); E=1e-180 COG: jhp0048_2; COG1012 NAD-dependent aldehyde dehydrogenases; E=1e-123 Cj1503c_1; COG0506 Proline dehydrogenase; E=2e-56 sll1561_2; COG1012 NAD-dependent aldehyde dehydrogenases; E=1e-51 PFAM: PF01619; Proline dehydrogenase; E=2e-36 PF00171; Aldehyde dehydrogenase family; E=0.0014; Belongs to the aldehyde dehydrogenase family.
   
  
 0.869
RB7221
Hypothetical protein.
       0.773
acs
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
  
 0.757
RB7217
Hypothetical protein.
       0.746
RB7219
Hypothetical protein.
       0.746
RB3967
Probable sodium/proline symporter (proline permease); PMID: 8031825 best DB hits: BLAST: gb:AAG20007.1; (AE005081) pantothenate permease; PanF; E=2e-20 pir:C69115; sodiumproline symporter (proline permease) -; E=3e-11 pir:B69833; metabolite permease homolog yhjB - Bacillus subtilis; E=7e-11 COG: VNG1785G; COG0591 Na+/proline, Na+/panthothenate symporters and; E=2e-21 panF; COG0591 Na+/proline, Na+/panthothenate symporters and related; E=3e-04 NMB0402; COG0591 Na+/proline, Na+/panthothenate symporters and; E=7e-04 PFAM: PF00474; Sodium:solute symporter family; E=0.11; Belongs to the sod [...]
 
    0.744
RB3349
Conserved hypothetical protein-putative sodium:solute symporter; PMID: 8905231 best DB hits: BLAST: pir:S75887; hypothetical protein - Synechocystis sp. (strain PCC; E=4e-40 gb:AAF54633.1; (AE003691) CG6723 gene product [Drosophila; E=5e-32 swissprot:Q9XT77; SL56_RABIT SODIUM-DEPENDENT MULTIVITAMIN; E=6e-32 COG: sll1087; COG0591 Na+/proline, Na+/panthothenate symporters and; E=4e-41 RP571; COG0591 Na+/proline, Na+/panthothenate symporters and related; E=4e-13 BH2222; COG0591 Na+/proline, Na+/panthothenate symporters and; E=3e-12 PFAM: PF01344; Kelch motif; E=0.014 PF00474; Sodium:solut [...]
 
    0.647
cht1
High affinity choline transporter; Best DB hits: BLAST: gb:AAG36945.1; (AF276872) sodium and chloride-dependent; E=8e-26 embl:CAC03719.1; (AJ401467) high affinity choline transporter; E=1e-25 ddbj:BAA90484.1; (AB030947) high-affinity choline transporter; E=2e-25 COG: PA1418; COG0591 Na+/proline, Na+/panthothenate symporters and; E=7e-20 panF; COG0591 Na+/proline, Na+/panthothenate symporters and related; E=3e-10 PFAM: PF00474; Sodium:solute symporter family; E=4.5e-05; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
    0.627
sphX
Phosphate ABC transporter, periplasmic phosphate-binding protein; PMID: 95075296 PMID: 7741855 best DB hits: BLAST: swissprot:P39665; SPHX_SYNP7 SPHX PROTEIN PRECURSOR -----pir:; E=9e-59 swissprot:Q55200; SPHX_SYNY3 SPHX PROTEIN HOMOLOG PRECURSOR; E=4e-56 gb:AAB89890.1; (AE001010) phosphate ABC transporter, periplasmic; E=3e-53 COG: sll0679; COG0226 ABC-type phosphate transport system, periplasmic; E=4e-57 PFAM: PF01449; Phosphate-binding protein; E=2.2e-64.
     
 0.622
sglT
Sodium/glucose cotransporter; PMID: 8652595 PMID: 10835424 best DB hits: BLAST: swissprot:P96169; SGLT_VIBPA SODIUMGLUCOSE COTRANSPORTER; E=5e-24 ddbj:BAA11215.1; (D78137) Na+glucose symporter [Vibrio; E=6e-22 ddbj:BAA22950.1; (AB008225) Na+-glucose cotransporter type 1; E=4e-16 COG: sll1087; COG0591 Na+/proline, Na+/panthothenate symporters and; E=3e-13 yidK; COG0591 Na+/proline, Na+/panthothenate symporters and related; E=1e-06 MTH1856; COG0591 Na+/proline, Na+/panthothenate symporters and; E=1e-06 PFAM: PF00474; Sodium:solute symporter family; E=0.0075; Belongs to the sodium:solute [...]
 
    0.617
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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