STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ctpA-2Carboxyl-terminal proteinase; PMID: 98196666 best DB hits: BLAST: pir:F70369; carboxyl-terminal proteinase - Aquifex aeolicus -----; E=4e-49 swissprot:Q44879; CTPA_BARBA CARBOXY-TERMINAL PROCESSING PROTEASE; E=7e-49 pir:B83005; probable carboxyl-terminal proteinase PA5134 [imported]; E=7e-47 COG: aq_797; COG0793 Periplasmic protease; E=3e-50 PFAM: PF00595; PDZ domain (Also known as DHR or GLG; E=0.0011; Belongs to the peptidase S41A family. (495 aa)    
Predicted Functional Partners:
RB7410
Putative histidine kinase (PhoR1); Best DB hits: BLAST: embl:CAB37946.1; (AJ133131) putative histidine kinase (PhoR1); E=2e-43 swissprot:P35164; RESE_BACSU SENSOR PROTEIN RESE -----pir:; E=7e-40 embl:CAB64973.1; (AJ012050) VicK protein [Enterococcus faecalis]; E=1e-38 COG: BH4026; COG0642 Sensory transduction histidine kinases; E=2e-39 PFAM: PF00989; PAS domain; E=0.0015 PF00512; His Kinase A (phosphoacceptor) doma; E=9.2e-20 PF02518; Histidine kinase-, DNA gyrase B-, p; E=7.3e-38.
 
     0.804
RB7409
Hypothetical protein.
       0.773
RB7411
Hypothetical protein.
       0.773
RB7412
Hypothetical protein-transmembrane prediction.
       0.572
pstA
Phosphate ABC transporter (permease); PMID: 99411980 best DB hits: BLAST: ddbj:BAB06711.1; (AP001517) phosphate ABC transporter (permease); E=1e-26 gb:AAB89888.1; (AE001010) phosphate ABC transporter, permease; E=1e-25 pir:D82504; phosphate ABC transporter, permease protein VCA0072; E=6e-17 COG: BH2992; COG0581 ABC-type phosphate transport system, permease; E=9e-28 MTH1729; COG0573 ABC-type phosphate transport system, permease; E=1e-16 sll0682; COG0581 ABC-type phosphate transport system, permease; E=4e-16 PFAM: PF00060; Ligand-gated ion channel; E=0.035 PF00528; Binding-protein-depend [...]
      
 0.563
TPX
Probable thiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
      
 0.550
merA
Mercuric reductase; PMID: 2536669 PMID: 2067577 best DB hits: BLAST: pir:S75167; mercuric reductase - Synechocystis sp. (strain PCC 6803); E=1e-121 embl:CAA70224.1; (Y09024) mercuric reductase [Bacillus cereus]; E=9e-60 pir:T44505; merA protein [imported] - Clostridium butyricum -----; E=3e-59 COG: slr1849; COG1249 Dihydrolipoamide dehydrogenase/glutathione; E=1e-122 PFAM: PF00732; GMC oxidoreductases; E=0.074 PF02254; KTN NAD-binding domain; E=0.7 PF00899; ThiF family; E=0.22.
      
 0.547
tadB
Conserved hypothetical protein; PMID: 10880436 best DB hits: BLAST: gb:AAF40196.1; AF229646_8 (AF229646) TadB [Caulobacter crescentus]; E=9e-20 pir:D83108; hypothetical protein PA4301 [imported] - Pseudomonas; E=6e-11 embl:CAB92603.1; (AL356813) putative integral membrane protein; E=7e-06 COG: PA4301; COG2064 Predicted membrane protein; E=5e-12.
      
 0.547
tadB-2
Probable protein secretion system or pilus assembly related protein TadB; PMID: 11029439 best DB hits: BLAST: gb:AAF40196.1; AF229646_8 (AF229646) TadB [Caulobacter crescentus]; E=0.005 gb:AAD38173.2; AF152598_2 (AF152598) TadB [Actinobacillus; E=0.41.
      
 0.547
cls
Cardiolipin synthase; PMID: 1663113 PMID: 9370333 best DB hits: BLAST: pir:B82971; cardiolipin synthase PA5394 [imported] - Pseudomonas; E=3e-42 swissprot:P71040; CLS2_BACSU PROBABLE CARDIOLIPIN SYNTHETASE 2; E=4e-42 swissprot:P31048; CLS_PSEPU PROBABLE CARDIOLIPIN SYNTHETASE; E=5e-42 COG: PA5394; COG1502; E=2e-43 cls; COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiol; E=9e-32 BS_ywjE; COG1502; E=2e-31 PFAM: PF00614; Phospholipase D. Active site motif; E=1.2e-05.
  
  
 0.547
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.