STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB7512Putative integral membrane transport protein; PMID: 97000351 PMID: 8559252 best DB hits: BLAST: embl:CAC16517.1; (AL450223) putative integral membrane transport; E=3e-41 pir:A82432; sodiumsolute symporter VCA0667 [imported] - Vibrio; E=4e-26 pir:S75887; hypothetical protein - Synechocystis sp. (strain PCC; E=2e-25 COG: VCA0667; COG0591 Na+/proline, Na+/panthothenate symporters and; E=4e-27 yidK; COG0591 Na+/proline, Na+/panthothenate symporters and related; E=2e-06 PA0287; COG0591 Na+/proline, Na+/panthothenate symporters and; E=2e-06 PFAM: PF00474; Sodium:solute symporter family; E=1. [...] (507 aa)    
Predicted Functional Partners:
RB7510
Hypothetical 460 kDa protein IN FEUA-SIGW intergenic region [Precursor]; PMID: 94281248 PMID: 8011666 PMID: 97419514 PMID: 9274029 best DB hits: BLAST: swissprot:P40407; YBBC_BACSU HYPOTHETICAL 46.0 KDA PROTEIN IN; E=6e-75 ddbj:BAB04393.1; (AP001509) BH0674~unknown conserved protein; E=3e-71 pir:G81651; conserved hypothetical protein TC0894 [imported] -; E=5e-47.
     0.973
RB1608
Putative esterase; PMID: 8843436 best DB hits: BLAST: embl:CAC16441.1; (AL450165) putative esterase [Streptomyces; E=2e-40 pir:A69744; beta-lactamase homolog ybbE - Bacillus subtilis -----; E=5e-37 embl:CAB94057.1; (AL358672) putative secreted protein; E=3e-32 COG: BS_ybbE; COG1680 Beta-lactamase class C and other penicillin binding; E=5e-38.
     0.913
putA
PMID: 96062224 best DB hits: BLAST: pir:H64526; proline dehydrogenase (EC 1.5.99.8); E=0.0 pir:B71980; proline dehydrogenase (EC 1.5.99.8); E=0.0 pir:C81297; proline dehydrogenase (EC 1.5.99.8); E=1e-180 COG: jhp0048_2; COG1012 NAD-dependent aldehyde dehydrogenases; E=1e-123 Cj1503c_1; COG0506 Proline dehydrogenase; E=2e-56 sll1561_2; COG1012 NAD-dependent aldehyde dehydrogenases; E=1e-51 PFAM: PF01619; Proline dehydrogenase; E=2e-36 PF00171; Aldehyde dehydrogenase family; E=0.0014; Belongs to the aldehyde dehydrogenase family.
  
  
 0.885
RB7509
Hypothetical protein-signal peptide and transmembrane prediction.
       0.642
RB7515
Conserved hypothetical protein-putative N-acetylglucosamine kinase; Best DB hits: BLAST: gb:AAF19757.1; AC009917_16 (AC009917) F26G16.16 [Arabidopsis; E=7e-24 embl:CAB71200.1; (AL138538) putative kinase [Streptomyces; E=6e-20 gb:AAF55174.1; (AE003708) CG6218 gene product [Drosophila; E=8e-12 COG: Ta0122; COG2971 Uncharacterized BCR; E=2e-06.
 
     0.632
murQ
Glucokinase regulatory protein-related protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate.
       0.594
cstA
Carbon starvation-induced protein; PMID: 99411980 best DB hits: BLAST: ddbj:BAB05512.1; (AP001513) carbon starvation-induced protein; E=3e-82 swissprot:O67304; CSTA_AQUAE CARBON STARVATION PROTEIN A HOMOLOG; E=5e-65 pir:E75032; carbon starvation protein A homolog PAB1554 [similarity]; E=1e-53 COG: BH1793; COG1966 Carbon starvation protein, predicted membrane; E=3e-83 yjiY; COG1966 Carbon starvation protein, predicted membrane protein; E=2e-47 jhp1095; COG1966 Carbon starvation protein, predicted membrane; E=3e-47 PFAM: PF02554; Carbon starvation protein CstA; E=2.2e-104.
  
    0.549
RB5641
Best DB hits: BLAST: pir:H81355; probable integral membrane protein Cj0832c [imported] -; E=2e-58 pir:D75220; hypothetical protein PAB2161 - Pyrococcus abyssi (strain; E=3e-54 pir:D71202; hypothetical protein PH1889 - Pyrococcus horikoshii; E=4e-52 COG: Cj0832c; COG1757 Na+/H+ antiporter; E=2e-59.
  
  
 0.530
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
  
 0.438
dagA
Putative Na(+)-linked D-alanine glycine permease; PMID: 1447975 best DB hits: BLAST: embl:CAC01597.1; (AL391041) putative amino acid transport; E=1e-90 gb:AAF12563.1; AE001826_32 (AE001826) Na(+)-linked D-alanine; E=5e-81 ddbj:BAB07752.1; (AP001520) amino acid transporter [Bacillus; E=4e-46 COG: DRB0133; COG1115 Na+/alanine symporter; E=4e-82 PFAM: PF02497; Arterivirus glycoprotein; E=0.45 PF00746; Gram positive anchor; E=0.031 PF01235; Sodium:alanine symporter fami; E=5.2e-96.
  
  
 0.407
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.