STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
natABest DB hits: BLAST: pir:C69049; ABC transporter (ATP-binding protein) - Methanobacterium; E=5e-47 swissprot:P46903; NATA_BACSU ATP-BINDING TRANSPORT PROTEIN NATA; E=2e-46 pir:F82572; sodium ABC transporter ATP-binding protein XF2329; E=5e-46 COG: MTH1370; COG1131 ABC-type multidrug transport system, ATPase; E=5e-48 PFAM: PF02223; Thymidylate kinase; E=0.42 PF00005; ABC transporter; E=1.6e-61. (273 aa)    
Predicted Functional Partners:
natB-2
Best DB hits: BLAST: pir:A75459; sodium extrusion protein NatB - Deinococcus radiodurans; E=2e-15 swissprot:P46904; NATB_BACSU PROTEIN NATB ----- pir: B69666; E=1e-10 ddbj:BAA22237.1; (AB000617) NatB [Bacillus subtilis]; E=5e-05 COG: DR0926; COG1668 ATP-dependent Na+ efflux pump membrane component; E=1e-16 BS_ydiL; COG1266 Predicted metal-dependent membrane protease; E=1e-04 PFAM: PF02517; CAAX amino terminal protease family; E=1.1e-19.
 
 
 0.988
natB
PMID: 10567266 best DB hits: BLAST: pir:A75459; sodium extrusion protein NatB - Deinococcus radiodurans; E=1e-09 swissprot:P46904; NATB_BACSU PROTEIN NATB -----pir: B69666; E=3e-07 ddbj:BAA22237.1; (AB000617) NatB [Bacillus subtilis]; E=0.002 COG: DR0926; COG1668 ATP-dependent Na+ efflux pump membrane component; E=1e-10 ybhS; COG0842 Permease component of an ABC-transporter; E=0.003 PFAM: PF02517; CAAX amino terminal protease family; E=1.8e-15.
 
 
 0.941
RB6469
Best DB hits: BLAST: pir:F82572; sodium ABC transporter ATP-binding protein XF2329; E=8e-44 swissprot:P46903; NATA_BACSU ATP-BINDING TRANSPORT PROTEIN NATA; E=2e-40 pir:B75459; sodium extrusion protein NatA - Deinococcus radiodurans; E=3e-39 COG: XF2329; COG1131 ABC-type multidrug transport system, ATPase; E=8e-45 ybhF; COG1131 ABC-type multidrug transport system, ATPase component; E=7e-32 PFAM: PF00448; SRP54-type protein, GTPase do; E=0.26 PF00005; ABC transporter; E=6.2e-51.
  
  
 
0.908
RB7632
Hypothetical protein.
       0.572
ksgA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
  
  
 0.547
rpsE
30S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.
  
     0.471
ftsH-3
Cell division protein FtsH homolog; Best DB hits: BLAST: swissprot:P72991; FTH4_SYNY3 CELL DIVISION PROTEIN FTSH HOMOLOG 4; E=5e-20 gb:AAG19776.1; (AE005063) cell division cycle protein; Cdc48b; E=9e-20 gb:AAF69154.1; AC007915_6 (AC007915) F27F5.8 [Arabidopsis; E=2e-19 COG: slr1604; COG0465 ATP-dependent Zn proteases; E=4e-21 VNG1472G; COG0464 ATPases of the AAA+ class; E=8e-21 PH0201; COG1222 ATP-dependent 26S proteasome regulatory subunit; E=3e-20 PFAM: PF01695; IstB-like ATP binding protein; E=0.25 PF00910; RNA helicase; E=0.35 PF00004; ATPase family associated with va; E=8.6e-30.
  
     0.466
cysS
cysteinyl-tRNA synthetase; PMID: 2014166 PMID: 1864365 best DB hits: BLAST: gb:AAK03029.1; (AE006134) CysS [Pasteurella multocida]; E=5e-91 swissprot:Q9KGF4; SYC_BACHD CYSTEINYL-TRNA SYNTHETASE; E=2e-89 swissprot:O58370; SYC_PYRHO CYSTEINYL-TRNA SYNTHETASE; E=3e-88 COG: BH0111; COG0215 Cysteinyl-tRNA synthetase; E=2e-90 PFAM: PF01406; tRNA synthetases class I (C); E=1.8e-122; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
   
 0.439
RB6045
Hypothetical protein-transmembrane prediction.
  
   0.429
RB6500
Mycocerosate synthase; PMID: 3880746 best DB hits: BLAST: pir:S72705; mycocerosate synthase (EC 2.3.1.111) - Mycobacterium; E=0.0 pir:H70819; probable polyketide synthase - Mycobacterium tuberculosis; E=0.0 gb:AAF62883.1; AF217189_6 (AF217189) epoD [Sorangium cellulosum]; E=1e-180 COG: PA2402_3; COG1020 Non-ribosomal peptide synthetase modules and related; E=4e-99 BS_ppsD_3; COG1020 Non-ribosomal peptide synthetase modules and; E=4e-92 PA2424_2; COG1020 Non-ribosomal peptide synthetase modules and related; E=1e-91 PFAM: PF00108; Thiolase, N-terminal domain; E=2.7e-06 PF00109; Beta-keto [...]
  
 
 0.412
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.