STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB7682Hypothetical protein. (495 aa)    
Predicted Functional Partners:
aroD
3-dehydroquinate dehydratase / shikimate 5-dehydrogenase precursor; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA); Belongs to the type-I 3-dehydroquinase family.
  
  
 0.656
rsfS
Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
  
  
 0.651
ribD
PMID: 9068650 best DB hits: BLAST: pir:T50546; riboflavin bifunctional biosynthesis protein ribG; E=2e-56 swissprot:P50853; RIBD_ACTPL RIBOFLAVIN BIOSYNTHESIS PROTEIN RIBD; E=2e-56 ddbj:BAB05273.1; (AP001512) riboflavin specific; E=9e-52 COG: ribD_1; COG0117 Pyrimidine deaminase; E=1e-28 BH1554_2; COG1985 Pyrimidine reductase, riboflavin biosynthesis; E=6e-21 CPn0871_1; COG0117 Pyrimidine deaminase; E=1e-20 PFAM: PF00383; Cytidine and deoxycytidylate de; E=1.5e-31 PF01872; RibD C-terminal domain; E=4e-33.
  
  
 0.604
RB9751
Hypothetical protein-signal peptide prediction.
  
     0.574
pcxB
PMID: 8407791 best DB hits: BLAST: pir:E83626; protocatechuate 3,4-dioxygenase, beta subunit PA0153; E=1e-14 pir:T35018; protocatechuate 3,4-dioxygenase beta chain -; E=1e-14 gb:AAF65837.1; AF253466_3 (AF253466) protocatechuate; E=3e-14 PFAM: PF00652; QXW lectin repeat; E=0.28 PF00775; Dioxygenase; E=3.6e-18.
       0.550
RB7681
Hypothetical protein.
       0.550
RB3971
Hypothetical protein-signal peptide and transmembrane prediction.
  
     0.507
nadE
Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
  
 0.469
trkH
PMID: 7896723 best DB hits: BLAST: gb:AAB90400.1; (AE001046) TRK potassium uptake system protein; E=8e-61 pir:G82037; potassium uptake protein TrkH VC2756 [imported] - Vibrio; E=4e-49 swissprot:P44843; TRKH_HAEIN TRK SYSTEM POTASSIUM UPTAKE PROTEIN; E=1e-46 COG: AF0839; COG0168 Trk-type K+ transport systems, membrane components; E=8e-62 NMB0661_2; COG0168 Trk-type K+ transport systems, membrane; E=1e-36 PA3210; COG0168 Trk-type K+ transport systems, membrane components; E=1e-36 PFAM: PF02386; Sodium transport protein; E=1.1e-54.
  
    0.456
RB7684
Hypothetical protein.
       0.456
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.