STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
arsA-5Arylsulfatase A; PMID: 7910580 PMID: 1572648 best DB hits: BLAST: gb:AAB03341.1; (U62317) arylsulfatase A [Homo sapiens]; E=4e-58 embl:CAA36398.1; (X52150) arylsulphatase a [Homo sapiens]; E=4e-58 pdb:1E2S; P Chain P, Crystal Structure Of An Arylsulfatase A; E=4e-57 COG: PA0183; COG3119 Arylsulfatase A and related enzymes; E=5e-25 PFAM: PF00884; Sulfatase; E=3.3e-84. (492 aa)    
Predicted Functional Partners:
RB7871
Hypothetical protein-signal peptide and transmembrane prediction; PMID: 12004073.
 
     0.826
RB3353
Sialidase [Precursor]; PMID: 1400240 PMID: 8591030 best DB hits: BLAST: swissprot:Q02834; NANH_MICVI SIALIDASE PRECURSOR (NEURAMINIDASE); E=3e-40 pdb:1EUR; Sialidase ----- pdb: 1EUS Sialidase Complexed; E=3e-40 pdb:1EUU; Sialidase Or Neuraminidase, Large 68kd Form -----; E=3e-40 PFAM: PF02012; BNR repeat; E=0.1.
  
 
  0.696
nanH
Neuraminidase precursor; PMID: 8093075 best DB hits: BLAST: ddbj:BAA05853.1; (D28493) neuraminidase precursor [Bacteroides; E=4e-90 pir:JC2500; exo-alpha-sialidase (EC 3.2.1.18) precursor -; E=8e-89 swissprot:P31206; NANH_BACFR SIALIDASE (NEURAMINIDASE) -----; E=2e-68 PFAM: PF02012; BNR repeat; E=0.038.
    
  0.650
GALNS-3
N-acetylgalactosamine-6-sulfate sulfatase; PMID: 20164110 best DB hits: BLAST: gb:AAF63858.1; (AF112242) N-acetylgalactosamine-6-sulfate; E=2e-35 ddbj:BAA04535.1; (D17629) N-acetylgalactosamine 6-sulfate; E=6e-35 gb:AAF30402.1; AF109924_1 (AF109924) sulfatase 1 precursor [Helix; E=2e-30 COG: ydeN; COG3119 Arylsulfatase A and related enzymes; E=2e-26 PA0924; COG3083 Predicted hydrolase of alkaline phosphatase; E=0.002 PFAM: PF00884; Sulfatase; E=3.3e-51.
 
    
0.616
RB7869
PMID: 8098033 best DB hits: BLAST: pir:D81057; GDSL lipase family protein NMB1674 [imported] -; E=4e-13 gb:AAG54851.1; AE005230_11 (AE005230) acyl-CoA thioesterase I; E=9e-11 swissprot:P29679; TESA_ECOLI ACYL-COA THIOESTERASE I PRECURSOR; E=2e-10 COG: NMB1674; COG2755 Lysophospholipase L1 and related esterases; E=3e-14 PFAM: PF00657; Lipase/Acylhydrolase with GDSL-li; E=0.59.
       0.572
RB7868
Conserved hypothetical protein-putative secreted protein; PMID: 97061201 best DB hits: BLAST: pir:S75290; hypothetical protein sll1289 - Synechocystis sp. (strain; E=3e-20 pir:G70687; hypothetical protein Rv1732c - Mycobacterium; E=1e-17 gb:AAF87891.1; AC015447_1 (AC015447) Hypothetical protein; E=1e-15 COG: sll1289; COG0526 Thiol-disulfide isomerase and thioredoxins; E=3e-21.
       0.564
RB6738
Hypothetical protein.
 
      0.485
RB2663
Heparan N-sulfatase; PMID: 11181566 best DB hits: BLAST: gb:AAG41945.1; AF304053_1 (AF304053) heparan N-sulfatase [Mus; E=5e-36 gb:AAG41946.1; AF304054_1 (AF304054) mutant heparan N-sulfatase; E=2e-35 gb:AAF29467.1; (AF156255) N-sulfoglucosamine sulfohydrolase [Mus; E=1e-34 COG: Rv0296c; COG3119 Arylsulfatase A and related enzymes; E=2e-27 VC2041; COG3083 Predicted hydrolase of alkaline phosphatase; E=0.003 aslA; COG3119 Arylsulfatase A and related enzymes; E=0.005 PFAM: PF00884; Sulfatase; E=3.3e-16 PF01974; tRNA intron endonuclease, catal; E=0.44 PF00884; Sulfatase; E=8.6e-21.
  
     0.439
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.