STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sigProbable ECF sigma factor AdsA; PMID: 20372644 best DB hits: BLAST: ddbj:BAB08177.1; (AB039273) ECF sigma factor AdsA [Streptomyces; E=2e-05 pir:T36271; probable RNA polymerase sigma factor - Streptomyces; E=2e-04 embl:CAB55345.1; (AJ010584) ECF sigma factor [Streptomyces; E=2e-04 COG: Rv3414c; COG1595 DNA-directed RNA polymerase specialized sigma; E=3e-05 TM0902; COG1191 DNA-directed RNA polymerase specialized sigma; E=3e-04 BS_sigH; COG1595 DNA-directed RNA polymerase specialized sigma; E=0.008 PFAM: PF00140; Sigma-70 factor; E=3.2e-05. (228 aa)    
Predicted Functional Partners:
ppkA-3
Serine/threonine protein kinase PpkA; PMID: 7883195 best DB hits: BLAST: gb:AAD03499.2; (AF035395) serinethreonine protein kinase PpkA; E=6e-16 pir:D83637; serinethreonine protein kinase PpkA PA0074 [imported] -; E=1e-15 pir:T36502; serinethreonine protein kinase - Streptomyces; E=2e-11 COG: PA0074; COG0515 Serine/threonine protein kinases; E=1e-16 PFAM: PF00069; Protein kinase domain; E=1e-08.
 
 
   0.720
RB12936
Conserved hypothetical protein; PMID: 10567266 best DB hits: BLAST: pir:H75280; conserved hypothetical protein - Deinococcus radiodurans; E=5e-27 swissprot:P71551; Y959_MYCTU HYPOTHETICAL 74.6 KDA PROTEIN RV0959; E=5e-21 gb:AAB89815.1; (AE001004) A. fulgidus predicted coding region; E=0.013 COG: AF1444; COG2304 Protein containing von Willebrand factor (vWF) type; E=0.001.
  
     0.620
RB2247
Conserved hypothetical protein; Best DB hits: BLAST: gb:AAG19229.1; (AE005019) Vng0754c [Halobacterium sp. NRC-1]; E=9e-06 gb:AAF75279.1; AF265353_1 (AF265353) byssal protein Dpfp1; E=0.21 ddbj:BAA94345.1; (AB035520) parchorin [Oryctolagus cuniculus]; E=0.50 PFAM: PF00089; Trypsin; E=0.58.
  
     0.615
RB10473
Best DB hits: BLAST: pir:D71687; alkaline proteinase secretion protein apre (aprE) RP314; E=0.032 pir:E82263; conserved hypothetical protein VC0913 [imported] -; E=0.053 gb:AAK03081.1; (AE006139) unknown [Pasteurella multocida]; E=0.13 COG: RP314; COG0845 Membrane-fusion protein; E=0.003 PFAM: PF01590; GAF domain; E=0.00029 PF00364; Biotin-requiring enzyme; E=0.0022.
  
     0.583
RB1508
Probable n-terminal acetyltransferase; PMID: 3106324 best DB hits: BLAST: pir:D75017; n-terminal acetyltransferase PAB1098 - Pyrococcus abyssi; E=4e-05 pir:A71455; probable acetyltransferase - Pyrococcus horikoshii; E=2e-04 embl:CAA51674.1; (X73149) Nourseothricin acetyltransferase; E=3e-04 COG: PAB1098; COG0456 Acetyltransferases; E=4e-06 BS_yobR; COG0454 Histone acetyltransferase HPA2 and related; E=1e-04 PA4678; COG0456 Acetyltransferases; E=5e-04 PFAM: PF00583; Acetyltransferase (GNAT) family; E=3.8e-21.
  
     0.574
RB7926
Hypothetical protein; Best DB hits: PFAM: PF00009; Elongation factor Tu family; E=0.29; Belongs to the sigma-70 factor family.
       0.531
RB1950
Hypothetical protein-signal peptide and transmembrane prediction.
  
     0.503
RB6095
Conserved hypothetical protein; PMID: 10484179 best DB hits: BLAST: ddbj:BAB04212.1; (AP001508) BH0493~unknown [Bacillus halodurans]; E=4e-12 gb:AAF77061.1; AF266466_3 (AF266466) putative hexuronic acid; E=0.003 gb:AAK05726.1; AE006393_5 (AE006393) glucuronate isomerase (EC; E=0.57.
  
     0.449
RB5968
Best DB hits: BLAST: pir:B72234; RNA polymerase sigma-E factor - Thermotoga maritima; E=0.42 gb:AAC14121.1; (AF056199) sigma factor E [Streptomyces; E=0.80 PFAM: PF00140; Sigma-70 factor; E=4.9e-05 PF00196; Bacterial regulatory proteins,; E=0.19.
  
     0.444
RB7603
Best DB hits: BLAST: pir:T23334; hypothetical protein K04H8.3 - Caenorhabditis elegans; E=0.53 PFAM: PF02321; Outer membrane efflux protein; E=0.0021.
  
     0.442
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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