STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB8290Conserved hypothetical protein-putative potassium channel; PMID: 8170937 best DB hits: BLAST: pir:S76018; hypothetical protein - Synechocystis sp. (strain PCC; E=2e-61 swissprot:Q58752; YD57_METJA PUTATIVE POTASSIUM CHANNEL PROTEIN; E=1e-36 swissprot:Q57604; Y13B_METJA PUTATIVE POTASSIUM CHANNEL PROTEIN; E=2e-34 COG: sll0536; COG1226 Kef-type K+ transport systems, predicted; E=1e-62 MJ1357; COG1226 Kef-type K+ transport systems, predicted NAD-binding; E=1e-37 MJ0138.1; COG1226 Kef-type K+ transport systems, predicted; E=2e-35 PFAM: PF00520; Ion transport protein; E=0.45 PF02254; KTN NA [...] (413 aa)    
Predicted Functional Partners:
trkH
PMID: 7896723 best DB hits: BLAST: gb:AAB90400.1; (AE001046) TRK potassium uptake system protein; E=8e-61 pir:G82037; potassium uptake protein TrkH VC2756 [imported] - Vibrio; E=4e-49 swissprot:P44843; TRKH_HAEIN TRK SYSTEM POTASSIUM UPTAKE PROTEIN; E=1e-46 COG: AF0839; COG0168 Trk-type K+ transport systems, membrane components; E=8e-62 NMB0661_2; COG0168 Trk-type K+ transport systems, membrane; E=1e-36 PA3210; COG0168 Trk-type K+ transport systems, membrane components; E=1e-36 PFAM: PF02386; Sodium transport protein; E=1.1e-54.
  
 
 0.892
moaE
Molybdopterin converting factor, large subunit; PMID: 8361352 PMID: 8514782 best DB hits: BLAST: gb:AAF67478.1; AF155659_1 (AF155659) molybdenum cofactor; E=6e-15 embl:CAB71291.1; (AJ271728) molybdopterin synthase, large subunit; E=1e-14 pir:D70487; molybdopterin biosynthesis protein E chain [similarity]; E=1e-13 COG: aq_2181; COG0314 Molybdopterin converting factor, large subunit; E=1e-14 PFAM: PF02391; Molydopterin converting factor subun; E=7.2e-26.
   
    0.606
uroD
Uroporphyrinogen III synthase, uroporhyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
    0.577
hemD
PMID: 7665501 best DB hits: BLAST: gb:AAK00606.1; AF221100_3 (AF221100) uroporphyrinogen III; E=1e-89 swissprot:Q59294; HEM4_CLOJO PORPHYRIN BIOSYNTHESIS PROTEIN HEMD; E=1e-64 gb:AAC18588.1; (AF064061) uroporphyrinogen-III; E=3e-63 COG: NMB1156_2; COG0007 Uroporphyrinogen-III methylase; E=2e-44 sll0166_2; COG1587 Uroporphyrinogen-III synthase; E=7e-30 PFAM: PF00590; Tetrapyrrole (Corrin/Porphyrin); E=1.2e-63 PF02602; Uroporphyrinogen-III synthase H; E=7.1e-43.
  
    0.547
RB1352
Hypothetical protein.
   
    0.540
nnrD
Conserved hypothetical protein-putative sugar kinase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
  
    0.530
RB11062
Conserved hypothetical protein.
 
     0.435
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
Server load: low (18%) [HD]