STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB8306Hypothetical protein-putative a gene in the purF operon involved in colicin V biosynthesis; PMID: 2542219 best DB hits: PFAM: PF02674; Colicin V production protein; E=8.4e-14. (265 aa)    
Predicted Functional Partners:
purF
Amidophosphoribosyltransferase [precursor]; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
  
 0.908
purC
Phosphoribosylaminoimidazole-succinocarboxamide synthase; PMID: 10710307 PMID: 8828210 best DB hits: BLAST: ddbj:BAA89448.1; (AB003161); E=3e-61 pir:G81943; probable phosphoribosylaminoimidazolesuccinocarboxamide; E=4e-60 pir:B81161; phosphoribosylaminoimidazole-succinocarboxamide synthase; E=1e-59 COG: NMB0757; COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide; E=1e-60 PFAM: PF01259; SAICAR synthetase; E=2.3e-21.
  
    0.857
purM
Phosphoribosylformylglycinamidine cyclo-ligase; PMID: 3015935 PMID: 3530323 best DB hits: BLAST: pir:S75786; phosphoribosylformylglycinamidine cyclo-ligase (EC; E=3e-82 ddbj:BAB04350.1; (AP001509) phosphoribosylaminoimidazole; E=7e-82 swissprot:P12043; PUR5_BACSU PHOSPHORIBOSYLFORMYLGLYCINAMIDINE; E=8e-77 COG: slr0838; COG0150 Phosphoribosylaminoimidazol (AIR) synthetase; E=3e-83 PFAM: PF00586; AIR synthase related protein, N-term; E=2.2e-55 PF02769; AIR synthase related protein, C-term; E=9.4e-36.
   
    0.850
purE
Phosphoribosylaminoimidazole carboxylase catalytic subunit (air carboxylase) (airc); Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
   
    0.817
pfaS
PMID: 10548741 best DB hits: BLAST: gb:AAB89983.1; (AE001017) phosphoribosylformylglycinamidine; E=2e-33 ddbj:BAA20816.1; (AB002359) KIAA0361 [Homo sapiens]; E=2e-26 swissprot:O15067; PUR4_HUMAN PHOSPHORIBOSYLFORMYLGLYCINAMIDINE; E=2e-26 COG: AF1260; COG0047 Phosphoribosylformylglycinamidine (FGAM) synthase,; E=1e-34 NMB1996_2; COG0047 Phosphoribosylformylglycinamidine (FGAM); E=3e-22 HI0752_2; COG0047 Phosphoribosylformylglycinamidine (FGAM) synthase,; E=1e-20.
   
    0.805
purL
Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...]
   
    0.779
RB8309
Hypothetical protein.
       0.773
RB6127
Hypothetical protein-signal peptide prediction; Best DB hits: PFAM: PF01842; ACT domain; E=0.55 PF00515; TPR Domain; E=0.051.
 
     0.764
RB6233
Hypothetical protein.
  
     0.751
RB1793
Conserved hypothetical protein; PMID: 10360571 best DB hits: BLAST: pir:F72424; hypothetical protein - Thermotoga maritima (strain MSB8); E=0.098.
  
     0.736
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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