STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
flhFPMID: 1447978 best DB hits: BLAST: pir:B72319; flagellar biosynthesis protein FlhF - Thermotoga; E=9e-32 ddbj:BAB06156.1; (AP001515) flagella-associated protein [Bacillus; E=3e-22 swissprot:Q01960; FLHF_BACSU FLAGELLAR BIOSYNTHESIS PROTEIN FLHF; E=2e-21 COG: TM0907; COG1419 Flagellar GTP-binding protein; E=8e-33 AF0622; COG0541 Signal recognition particle GTPase; E=3e-09 PFAM: PF00005; ABC transporter; E=0.018 PF00931; NB-ARC domain; E=0.2 PF00004; ATPase family associated with va; E=0.13. (464 aa)    
Predicted Functional Partners:
flhA
Flagella-associated protein; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
 
  
 0.978
RB10924
Probable sensor/response regulator hybrid; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
  
 
 0.961
RB4511
Sensory transduction histidine kinase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
  
 
 0.961
RB10479
Conserved hypothetical protein-putative transmembrane protein; Best DB hits: BLAST: pir:F70091; hypothetical protein yydH - Bacillus subtilis -----; E=2e-06 pir:H70326; hypothetical protein aq_294 - Aquifex aeolicus -----; E=0.29 PFAM: PF02163; Sterol-regulatory element bindi; E=0.039.
  
 
 0.955
flgE
Flagellar hook protein FlgE; PMID: 10368149 best DB hits: BLAST: gb:AAD24206.1; AF049342_4 (AF049342) flagellar hook protein FlgE; E=8e-22 gb:AAA61738.1; (U19712) flagellar hook polypeptide [Borrelia; E=1e-21 gb:AAA91361.1; (U12870) flagellar distal rod protein [Borrelia; E=3e-21 COG: BB0283; COG1749 Flagellar basal body and hook proteins; E=5e-22 PFAM: PF00460; Flagella basal body rod protein; E=3.7e-10.
 
  
 0.955
fliM
Flagellar motor switch protein fliM; PMID: 96345631 PMID: 8755894 best DB hits: BLAST: swissprot:P74927; FLIM_TREPA FLAGELLAR MOTOR SWITCH PROTEIN FLIM; E=7e-47 swissprot:Q57511; FLIM_BORBU FLAGELLAR MOTOR SWITCH PROTEIN FLIM; E=5e-46 ddbj:BAB06165.1; (AP001515) flagellar motor switch protein; E=3e-44 COG: TP0721; COG1868 Flagellar motor switch protein; E=7e-48 PFAM: PF02154; Flagellar motor switch protein FliM; E=1.3e-68 PF01052; Surface presentation of antigens (S; E=0.19.
 
 
 0.952
fliG-2
Flagellar motor switch protein fliG; PMID: 10440379 best DB hits: BLAST: swissprot:Q9WY63; FLIG_THEMA FLAGELLAR MOTOR SWITCH PROTEIN FLIG; E=3e-60 pir:G71328; probable flagellar motor switch protein (fliG-2) -; E=2e-57 swissprot:P23448; FLIG_BACSU FLAGELLAR MOTOR SWITCH PROTEIN FLIG; E=5e-57 COG: TM0220; COG1536 Flagellar motor switch protein; E=3e-61 PFAM: PF01706; FliG C-terminal domain; E=7.8e-45.
 
 
 0.925
whiG
RNA polymerase sigma factor whiG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.904
flhB
PMID: 8299954 best DB hits: BLAST: pir:I40395; flagellar biosynthetic protein FlhB - Bacillus subtilis; E=7e-51 swissprot:P35538; FLHB_BACSU FLAGELLAR BIOSYNTHETIC PROTEIN FLHB; E=7e-51 pir:D72319; flagellar biosynthetic protein flhB TM0909 - Thermotoga; E=6e-46 COG: BS_flhB; COG1377 Flagellar biosynthesis/type III secretory pathway; E=6e-52 TM1672; COG2257 Uncharacterized BCR homologous to the cytoplasmic; E=9e-10 PFAM: PF01312; FlhB HrpN YscU SpaS Family; E=1.4e-91.
 
  
 0.880
fliG
Flagellar motor switch protein FliG; PMID: 10440379 best DB hits: BLAST: swissprot:Q9WY63; FLIG_THEMA FLAGELLAR MOTOR SWITCH PROTEIN FLIG; E=7e-08 pir:G71328; probable flagellar motor switch protein (fliG-2) -; E=6e-07 gb:AAF35852.1; AF220006_1 (AF220006) lateral flagellar motor; E=2e-06 COG: TM0220; COG1536 Flagellar motor switch protein; E=7e-09.
 
 
 0.871
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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