STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GALNS-6Probable sulfatase atsG; PMID: 9634230 best DB hits: BLAST: gb:AAF63858.1; (AF112242) N-acetylgalactosamine-6-sulfate; E=8e-20 ddbj:BAA04535.1; (D17629) N-acetylgalactosamine 6-sulfate; E=3e-18 pir:F70837; probable sulfatase (EC 3.1.6.-) atsG - Mycobacterium; E=2e-15 COG: Rv0296c; COG3119 Arylsulfatase A and related enzymes; E=2e-16 BS_yvgJ; COG1368 Phosphoglycerol transferase and related proteins,; E=0.001 PAB0793; COG2194 Predicted membrane-associated, metal-dependent; E=0.002 PFAM: PF01663; Type I phosphodiesterase / nucle; E=0.89 PF00884; Sulfatase; E=7.3e-28. (483 aa)    
Predicted Functional Partners:
mdsA
PMID: 10809675 best DB hits: BLAST: gb:AAF72520.1; AF248951_1 (AF248951) mucin-desulfating sulfatase; E=2e-56 pir:T44602; phosphonate monoester hydrolase (EC 3.1.3.-) PEH; E=3e-30 pir:F83354; probable sulfatase PA2333 [imported] - Pseudomonas; E=1e-26 COG: PA2333; COG3119 Arylsulfatase A and related enzymes; E=9e-28 PAB0793; COG2194 Predicted membrane-associated, metal-dependent; E=9e-08 VC2600; COG3083 Predicted hydrolase of alkaline phosphatase; E=9e-07 PFAM: PF00884; Sulfatase; E=2.6e-65.
 
    
0.829
rne
Ribonuclease E; PMID: 2011493 PMID: 8415644 PMID: 11328869 best DB hits: BLAST: pir:B82538; ribonuclease E XF2607 [imported] - Xylella fastidiosa; E=1e-100 pir:H83273; ribonuclease E PA2976 [imported] - Pseudomonas; E=7e-97 gb:AAK03075.1; (AE006138) Rne [Pasteurella multocida]; E=2e-95 COG: XF2607; COG1530 Ribonucleases G and E; E=1e-101 PFAM: PF00575; S1 RNA binding domain; E=3.6e-07.
       0.773
fdhF
Formate dehydrogenase-like protein; PMID: 2941757 PMID: 2211698 PMID: 9036855 best DB hits: BLAST: gb:AAC44462.1; (U60056) CbbBc [Ralstonia eutropha]; E=7e-98 pir:T35749; probable formate dehydrogenase - Streptomyces coelicolor; E=8e-96 pir:A82998; probable oxidoreductase PA5181 [imported] - Pseudomonas; E=7e-93 COG: PA5181; COG0243 Anaerobic dehydrogenases, typically; E=6e-94 MTH1552; COG3383 Uncharacterized anaerobic dehydrogenase; E=9e-45 PH1353; COG0243 Anaerobic dehydrogenases, typically; E=7e-38 PFAM: PF00384; Molybdopterin oxidoreductases; E=2e-36 PF01568; Molydopterin dinucleot [...]
       0.705
acrB
Acriflavine resistance protein B; PMID: 8905231 PMID: 8407802 PMID: 7651136 best DB hits: BLAST: pir:F83335; RND multidrug efflux transporter MexF PA2494 [imported] -; E=0.0 pir:T30830; hypothetical protein mexF - Pseudomonas aeruginosa -----; E=0.0 pir:D83206; probable RND efflux transporter PA3522 [imported] -; E=0.0 COG: PA2494; COG0841 Cation/multidrug efflux pump; E=0.0 PFAM: PF00873; AcrB/AcrD/AcrF family; E=0; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
      
 0.550
RB950
Amino acid transporter; PMID: 3146645 best DB hits: BLAST: swissprot:Q10858; YJ99_MYCTU HYPOTHETICAL 45.3 KDA TRANSPORT; E=2e-23 embl:CAB76881.1; (AL159139) putative amino acid transporter; E=2e-16 pir:G82809; amino acid transporter XF0408 [imported] - Xylella; E=3e-15 COG: Rv1999c; COG0531 Amino acid transporters; E=2e-24 BS_gabP; COG1113 Gamma-aminobutyrate and related permeases; E=2e-06 Rv3253c; COG0531 Amino acid transporters; E=4e-06 PFAM: PF00324; Amino acid permease; E=0.00042.
      
 0.543
RB8590
Hypothetical protein.
       0.511
ptsI
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
       0.511
RB8592
Best DB hits: BLAST: pir:S77440; hypothetical protein sll1084 - Synechocystis sp. (strain; E=2e-14 embl:CAB75381.1; (AL139298) hypothetical protein SCC88.11c; E=6e-09 pir:E72374; hypothetical protein - Thermotoga maritima (strain; E=4e-05 COG: sll1084; COG1032 Fe-S oxidoreductases family 2; E=2e-15 PFAM: PF02474; Nodulation protein A (NodA); E=0.78.
       0.511
RB3324
Hypothetical protein-signal peptide and transmembrane prediction; PMID: 12004073.
  
     0.501
RB2732
Heparan N-sulfatase; PMID: 11181566 best DB hits: BLAST: gb:AAG41945.1; AF304053_1 (AF304053) heparan N-sulfatase [Mus; E=9e-29 gb:AAF29467.1; (AF156255) N-sulfoglucosamine sulfohydrolase [Mus; E=2e-28 gb:AAG41946.1; AF304054_1 (AF304054) mutant heparan N-sulfatase; E=3e-28 COG: Rv0296c; COG3119 Arylsulfatase A and related enzymes; E=9e-29 TM1703; COG1368 Phosphoglycerol transferase and related proteins,; E=2e-04 yejM; COG3083 Predicted hydrolase of alkaline phosphatase; E=0.001 PFAM: PF00884; Sulfatase; E=2.2e-23.
  
   
0.479
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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