STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB8615Best DB hits: BLAST: pir:E69869; thioredoxin related protein ykvV - Bacillus subtilis; E=1e-07 pir:E69891; cytochrome c biogenesis protein CycX homolog homolog; E=4e-07 swissprot:P43221; TLPA_BRAJA THIOL:DISULFIDE INTERCHANGE PROTEIN; E=3e-06 COG: BS_ykvV; COG0526 Thiol-disulfide isomerase and thioredoxins; E=9e-09 PFAM: PF02369; Bacterial Ig-like domain (group 1); E=0.033. (788 aa)    
Predicted Functional Partners:
RB4417
Cytochrome-c oxidase chain II/c precursor; PMID: 89231697 PMID: 91161592 best DB hits: BLAST: pir:A23711; cytochrome-c oxidase (EC 1.9.3.1) chain IIc precursor -; E=3e-42 swissprot:Q04441; COX2_BACFI CYTOCHROME C OXIDASE POLYPEPTIDE II; E=5e-38 ddbj:BAB06334.1; (AP001516) cytochrome caa3 oxidase (subunit II); E=2e-35 COG: BH2615_1; COG1622 Heme/copper-type cytochrome/quinol oxidases,; E=2e-21 XF1390; COG1622 Heme/copper-type cytochrome/quinol oxidases, subunit; E=1e-14 slr1136; COG1622 Heme/copper-type cytochrome/quinol oxidases,; E=3e-14 PFAM: PF00116; Cytochrome C oxidase subunit II, [...]
   
 
 0.884
RB8622
Hypothetical protein-transmembrane prediction.
       0.773
RB8625
Hypothetical protein-signal peptide and transmembrane prediction.
       0.773
ccsA
PMID: 7610180 PMID: 8617725 best DB hits: BLAST: pir:D81040; cytochrome c-type biogenesis protein, probable NMB1803; E=2e-18 pir:B81986; probable membrane protein NMA0660 [imported] - Neisseria; E=2e-18 pir:H71862; probable cytochrome C-type biogenesis protein -; E=7e-17 COG: NMB1803; COG0755 Cytochrome c-type biogenesis protein (heme exporter; E=2e-19 APE2274; COG1138 Cytochrome c biogenesis factor; E=5e-04 NMB1804; COG1333 ResB protein required for cytochrome c biosynthesis; E=0.002 PFAM: PF02590; Uncharacterized ACR, COG1576; E=0.15 PF01578; Cytochrome C assembly protein; E=0.036.
  
  
 0.725
RB5697
Probable thiol-disulfide interchange protein; PMID: 8384715 best DB hits: BLAST: swissprot:P14312; FIXW_RHILE FIXW PROTEIN ----- pir: JQ0313; E=3e-11 pir:C70314; thiol-disulfide interchange protein tlpA [imported] -; E=5e-06 ddbj:BAB05296.1; (AP001512) cytochrome c biogenesis (thioredoxin); E=6e-05 COG: aq_152; COG0526 Thiol-disulfide isomerase and thioredoxins; E=5e-07 PFAM: PF00085; Thioredoxin; E=1.9e-05.
  
     0.703
fixW
Probable FixW protein; PMID: 2555670 PMID: 2137818 best DB hits: BLAST: swissprot:P14312; FIXW_RHILE FIXW PROTEIN ----- pir: JQ0313; E=7e-12 swissprot:P36893; HELX_RHOCA THIOL:DISULFIDE INTERCHANGE PROTEIN; E=1e-08 pir:C70314; thiol-disulfide interchange protein tlpA [imported] -; E=3e-05 COG: aq_152; COG0526 Thiol-disulfide isomerase and thioredoxins; E=3e-06 PFAM: PF00085; Thioredoxin; E=4.6e-05.
  
     0.657
ubiG
PMID: 1479344 best DB hits: BLAST: pir:C83249; 3-demethylubiquinone-9 3-methyltransferase PA3171; E=0.004 swissprot:P08442; YAT1_SYNP6 ATP SYNTHASE SUBUNITS REGION ORF 1; E=0.055 pir:S76629; hypothetical protein - Synechocystis sp. (strain PCC; E=0.19 COG: PA3171; COG2227; E=3e-04.
   
   0.586
pfaS
PMID: 10548741 best DB hits: BLAST: gb:AAB89983.1; (AE001017) phosphoribosylformylglycinamidine; E=2e-33 ddbj:BAA20816.1; (AB002359) KIAA0361 [Homo sapiens]; E=2e-26 swissprot:O15067; PUR4_HUMAN PHOSPHORIBOSYLFORMYLGLYCINAMIDINE; E=2e-26 COG: AF1260; COG0047 Phosphoribosylformylglycinamidine (FGAM) synthase,; E=1e-34 NMB1996_2; COG0047 Phosphoribosylformylglycinamidine (FGAM); E=3e-22 HI0752_2; COG0047 Phosphoribosylformylglycinamidine (FGAM) synthase,; E=1e-20.
  
    0.574
RB11923
Conserved hypothetical protein-putative SCO1/SenC; PMID: 1944230 PMID: 7592491 best DB hits: BLAST: ddbj:BAB07054.1; (AP001518) BH3335~unknown conserved protein; E=6e-19 swissprot:P54178; YPMQ_BACSU HYPOTHETICAL 21.6 KDA PROTEIN IN ILVA; E=1e-12 ddbj:BAB06623.1; (AP001517) BH2904~unknown conserved protein; E=2e-12 COG: BH3335; COG1999 Uncharacterized protein SCO1/SenC/PrrC, involved in; E=6e-20 BH2868; COG0526 Thiol-disulfide isomerase and thioredoxins; E=1e-04 DR1886; COG1999 Uncharacterized protein SCO1/SenC/PrrC, involved in; E=2e-04 PFAM: PF02630; SCO1/SenC; E=1.7e-14.
  
   0.525
RB8628
Hypothetical protein.
       0.519
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.