STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB8857Conserved hypothetical protein-putative methyltransferase; Best DB hits: BLAST: pir:D75587; hypothetical protein - Deinococcus radiodurans (strain; E=5e-04 pir:F75277; ubiquinonemenaquinone biosynthesis methyltransferase -; E=0.11 COG: DRA0327; COG0500 SAM-dependent methyltransferases; E=5e-05. (251 aa)    
Predicted Functional Partners:
chsA
Probable chalcone synthase; PMID: 8108524 best DB hits: BLAST: pir:C75587; probable chalcone synthase - Deinococcus radiodurans; E=5e-46 pir:A75315; probable chalcone synthase - Deinococcus radiodurans; E=3e-35 gb:AAD43969.1; AF121274_1 (AF121274) putative chalcone synthase; E=1e-33 COG: DRA0326; COG0332 3-oxoacyl-[acyl-carrier-protein] synthase III; E=5e-47 PFAM: PF00195; Chalcone and stilbene synthas; E=1.3e-28 PF02797; Chalcone and stilbene synthas; E=2.9e-25.
 
     0.945
RB8854
Conserved hypothetical protein-putative FAD-containing oxidoreductase; Best DB hits: BLAST: pir:D70549; hypothetical protein Rv0561c - Mycobacterium; E=0.12 PFAM: PF02737; 3-hydroxyacyl-CoA dehydrogenase; E=0.26 PF01494; FAD binding domain; E=0.039 PF00070; Pyridine nucleotide-disulphide; E=2.9e-09.
 
     0.918
ldhA
PMID: 9025293 best DB hits: BLAST: pir:D83529; D-lactate dehydrogenase (fermentative) PA0927 [imported]; E=3e-95 pir:S76782; D-2-hydroxy-acid dehydrogenase (EC 1.1.99.6) -; E=1e-91 swissprot:P52643; LDHD_ECOLI D-LACTATE DEHYDROGENASE (D-LDH); E=1e-86 COG: PA0927; COG1052 Lactate dehydrogenase and related dehydrogenases; E=3e-96 PAB0514; COG0111 Phosphoglycerate dehydrogenase and related; E=3e-37 TP0037; COG1052 Lactate dehydrogenase and related dehydrogenases; E=5e-37 PFAM: PF00389; D-isomer specific 2-hydroxyacid; E=1.4e-24 PF02891; MIZ zinc finger; E=0.34 PF02826; D-isomer specific 2 [...]
       0.773
ubiE-3
Similar to ubiquinone/menaquinone biosynthesis methyltransferase UbiE; Best DB hits: BLAST: gb:AAK03770.1; (AE006205) UbiE [Pasteurella multocida]; E=0.011 embl:CAB86120.1; (AL163003) putative spermidine synthase; E=0.050 pir:G83392; hypothetical protein PA2034 [imported] - Pseudomonas; E=0.098.
 
     0.735
lgt
Probable prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.
       0.554
RB8849
Hypothetical protein-putative transmembrane protein.
       0.550
hpaG
Probable 2-hydroxyhepta-2,4-diene-1,7-dioate isomaerase; PMID: 8550403 best DB hits: BLAST: embl:CAC24092.1; (AL512982) hypothetical [Sulfolobus; E=1e-48 embl:CAB55723.1; (AL117387) hypothetical protein SCF41.20c; E=3e-18 pir:T45421; probable 2-hydroxyhepta-2,4-diene-1,7-dioate isomaerase; E=1e-10 COG: Rv2993c; COG0179 2-keto-4-pentenoate; E=2e-11 PFAM: PF01557; Fumarylacetoacetate (FAA) hydro; E=0.0074.
       0.550
RB8846
Hypothetical protein.
       0.549
RB6500
Mycocerosate synthase; PMID: 3880746 best DB hits: BLAST: pir:S72705; mycocerosate synthase (EC 2.3.1.111) - Mycobacterium; E=0.0 pir:H70819; probable polyketide synthase - Mycobacterium tuberculosis; E=0.0 gb:AAF62883.1; AF217189_6 (AF217189) epoD [Sorangium cellulosum]; E=1e-180 COG: PA2402_3; COG1020 Non-ribosomal peptide synthetase modules and related; E=4e-99 BS_ppsD_3; COG1020 Non-ribosomal peptide synthetase modules and; E=4e-92 PA2424_2; COG1020 Non-ribosomal peptide synthetase modules and related; E=1e-91 PFAM: PF00108; Thiolase, N-terminal domain; E=2.7e-06 PF00109; Beta-keto [...]
   
 
 0.415
RB11975
Polyketide synthase; PMID: 10662695 PMID: 10649995 best DB hits: BLAST: gb:AAF26921.1; AF210843_18 (AF210843) polyketide synthase [Sorangium; E=0.0 gb:AAF26923.1; AF210843_20 (AF210843) polyketide synthase [Sorangium; E=0.0 gb:AAF62883.1; AF217189_6 (AF217189) epoD [Sorangium cellulosum]; E=0.0 COG: BS_fabD; COG0331 (acyl-carrier-protein) S-malonyltransferase; E=7e-31 PA2965; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase I; E=3e-28 PA5234; COG0604 NADPH:quinone reductase and related Zn-dependent; E=2e-27 PFAM: PF00108; Thiolase, N-terminal domain; E=7.3e-07 PF00109; Beta-ketoacyl s [...]
   
 
 0.401
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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