STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nanHNeuraminidase precursor; PMID: 8093075 best DB hits: BLAST: ddbj:BAA05853.1; (D28493) neuraminidase precursor [Bacteroides; E=4e-90 pir:JC2500; exo-alpha-sialidase (EC 3.2.1.18) precursor -; E=8e-89 swissprot:P31206; NANH_BACFR SIALIDASE (NEURAMINIDASE) -----; E=2e-68 PFAM: PF02012; BNR repeat; E=0.038. (418 aa)    
Predicted Functional Partners:
RB3353
Sialidase [Precursor]; PMID: 1400240 PMID: 8591030 best DB hits: BLAST: swissprot:Q02834; NANH_MICVI SIALIDASE PRECURSOR (NEURAMINIDASE); E=3e-40 pdb:1EUR; Sialidase ----- pdb: 1EUS Sialidase Complexed; E=3e-40 pdb:1EUU; Sialidase Or Neuraminidase, Large 68kd Form -----; E=3e-40 PFAM: PF02012; BNR repeat; E=0.1.
  
  
 
0.926
RB3348
N-acylglucosamine 2-epimerase; PMID: 1723410 PMID: 1400260 best DB hits: BLAST: pir:S75649; renin-binding protein-related protein - Synechocystis; E=1e-68 pdb:1FP3; A Chain A, Crystal Structure Of N-Acyl-D-Glucosamine; E=4e-54 swissprot:P51607; RNBP_RAT N-ACYLGLUCOSAMINE 2-EPIMERASE (GLCNAC; E=2e-53 COG: slr1975; COG2942 N-acyl-D-glucosamine 2-epimerase; E=1e-69.
 
   
 0.831
nanA
Probable N-acetylneuraminate lyase; PMID: 8081752 PMID: 3909108 PMID: 10952301 best DB hits: BLAST: pir:E82157; probable N-acetylneuraminate lyase VC1776 [imported] -; E=2e-39 embl:CAC27797.1; (AJ271330) acylneuraminate lyase [Sus scrofa]; E=7e-36 gb:AAG18989.1; (AE004999) dihydrodipicolinate synthase; DapA; E=2e-18 COG: VC1776; COG0329 Dihydrodipicolinate synthetase/N-acetylneuraminate; E=2e-40 PFAM: PF00701; Dihydrodipicolinate synthetase famil; E=2.7e-23.
 
   
 0.802
RB12325
Arylsulfatase A precursor; PMID: 7910580 best DB hits: BLAST: swissprot:P50428; ARSA_MOUSE ARYLSULFATASE A PRECURSOR (ASA); E=7e-41 embl:CAA36398.1; (X52150) arylsulphatase a [Homo sapiens]; E=1e-40 gb:AAB03341.1; (U62317) arylsulfatase A [Homo sapiens]; E=1e-40 COG: aslA; COG3119 Arylsulfatase A and related enzymes; E=3e-26 PFAM: PF00884; Sulfatase; E=4.1e-39.
  
 
  0.777
RB409
Arylsulfatase A precursor; PMID: 7910580 best DB hits: BLAST: swissprot:P50428; ARSA_MOUSE ARYLSULFATASE A PRECURSOR (ASA); E=2e-38 gb:AAF63858.1; (AF112242) N-acetylgalactosamine-6-sulfate; E=7e-38 gb:AAC27821.1; (AF013158) arylsulfatase [Heliocidaris; E=1e-37 COG: ydeN; COG3119 Arylsulfatase A and related enzymes; E=2e-25 yejM; COG3083 Predicted hydrolase of alkaline phosphatase; E=1e-05 Rv0296c; COG3119 Arylsulfatase A and related enzymes; E=3e-05 PFAM: PF00884; Sulfatase; E=1.5e-38 PF00391; PEP-utilizing enzyme, mobile do; E=0.65 PF00884; Sulfatase; E=4.6e-44.
  
 
  0.754
RB12432
Arylsulfatase A precursor; PMID: 7910580 best DB hits: BLAST: swissprot:P50428; ARSA_MOUSE ARYLSULFATASE A PRECURSOR (ASA); E=5e-36 gb:AAC27821.1; (AF013158) arylsulfatase [Heliocidaris; E=7e-36 embl:CAA34667.1; (X16679) arylsulfatase [Hemicentrotus; E=1e-35 COG: aslA; COG3119 Arylsulfatase A and related enzymes; E=8e-28 PAB0793; COG2194 Predicted membrane-associated, metal-dependent; E=0.001 VNG1337C; COG3119 Arylsulfatase A and related enzymes; E=0.004 PFAM: PF00884; Sulfatase; E=2.2e-39.
  
 
  0.727
RB5146
PMID: 7910580 best DB hits: BLAST: embl:CAA36398.1; (X52150) arylsulphatase a [Homo sapiens]; E=6e-46 gb:AAB03341.1; (U62317) arylsulfatase A [Homo sapiens]; E=6e-46 swissprot:P50428; ARSA_MOUSE ARYLSULFATASE A PRECURSOR (ASA); E=2e-45 COG: aslA; COG3119 Arylsulfatase A and related enzymes; E=4e-22 PFAM: PF01069; Fatty acid desaturase; E=0.82 PF00884; Sulfatase; E=1.4e-38.
  
 
  0.723
RB5468
Hypothetical protein-signal peptide and transmembrane prediction; PMID: 10567266 best DB hits: PFAM: PF00561; alpha/beta hydrolase fold; E=0.1.
 
     0.662
arsA
Arylsulfatase A; PMID: 7910580 PMID: 1572648 best DB hits: BLAST: embl:CAA36398.1; (X52150) arylsulphatase a [Homo sapiens]; E=4e-61 gb:AAB03341.1; (U62317) arylsulfatase A [Homo sapiens]; E=4e-61 pdb:1E2S; P Chain P, Crystal Structure Of An Arylsulfatase A; E=4e-60 COG: PA0183; COG3119 Arylsulfatase A and related enzymes; E=5e-33 PFAM: PF00884; Sulfatase; E=3.7e-106.
 
  
  0.650
RB13147
PMID: 7910580 best DB hits: BLAST: embl:CAA36398.1; (X52150) arylsulphatase a [Homo sapiens]; E=7e-62 gb:AAB03341.1; (U62317) arylsulfatase A [Homo sapiens]; E=7e-62 gb:AAF63858.1; (AF112242) N-acetylgalactosamine-6-sulfate; E=3e-61 COG: aslA; COG3119 Arylsulfatase A and related enzymes; E=5e-31 PFAM: PF00884; Sulfatase; E=1.2e-107.
    
  0.650
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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