STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB9029Probable zinc metalloproteinase; PMID: 10571076 best DB hits: BLAST: embl:CAB08809.1; (Z95398) unknown [Mycobacterium leprae]; E=1e-152 pir:C70838; probable zinc metalloproteinase Rv0198c - Mycobacterium; E=1e-150 ddbj:BAA24495.1; (AB010440) PepO [Porphyromonas gingivalis]; E=1e-142 PFAM: PF01447; Thermolysin metallopeptidase, c; E=0.64 PF01431; Peptidase family M13; E=1.3e-88. (759 aa)    
Predicted Functional Partners:
truA
tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
 
      0.592
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.588
RB12337
Prolyl endopeptidase; PMID: 8370677 best DB hits: BLAST: pir:B75267; prolyl endopeptidase - Deinococcus radiodurans (strain; E=0.0 gb:AAD34991.1; (AF143951) prolyl endopeptidase [Aeromonas; E=1e-173 gb:AAF02211.1; (AF065429) prolyl endopeptidase [Aeromonas; E=1e-173 COG: DR2503; COG1505 Serine proteases of the peptidase family S9A; E=0.0 PA1304; COG1770 Protease II (serine protease PtrB); E=7e-45 NMB1877; COG1505 Serine proteases of the peptidase family S9A; E=2e-38 PFAM: PF02897; Prolyl oligopeptidase, N-termi; E=2.7e-149 PF00326; Prolyl oligopeptidase family; E=2.6e-40.
  
  
 0.571
RB9026
Probable NADH-dependent dyhydrogenase; Best DB hits: BLAST: swissprot:O05389; YRBE_BACSU HYPOTHETICAL 37.8 KDA PROTEIN IN; E=2e-08 swissprot:P40332; YISS_BACSU HYPOTHETICAL 37.5 KD PROTEIN IN; E=1e-07 ddbj:BAB04967.1; (AP001511) NADH-dependent dyhydrogenase; E=1e-06 COG: BS_yrbE; COG0673 Predicted dehydrogenases and related proteins; E=2e-09 PFAM: PF01408; Oxidoreductase family, NAD-bin; E=3.2e-25.
       0.563
ruvB
Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
   
    0.552
RB10078
Conserved hypothetical protein; Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.
  
     0.526
pepN
Probable aminopeptidase; PMID: 1765107 best DB hits: BLAST: embl:CAC16707.1; (AL450289) putative metallopeptidase; E=2e-08 gb:AAB68919.1; (U00062) Aap1'p: argininealanine aminopeptidase; E=8e-05 swissprot:P32454; APE2_YEAST AMINOPEPTIDASE II (YSCII) -----; E=1e-04 COG: YHR047c; COG0308 Aminopeptidase N; E=8e-06.
 
   
 0.514
RB9030
Hypothetical protein-transmembrane prediction.
       0.481
pepT2
Oligopeptide transporter, kidney isoform; PMID: 8639691 best DB hits: BLAST: swissprot:Q63424; PET2_RAT OLIGOPEPTIDE TRANSPORTER, KIDNEY; E=4e-47 prf:2113198A; Hpeptide cotransporter [Homo sapiens]; E=7e-47 gb:AAF66614.1; AF142441_1 (AF142441) H+oligopeptide symporter; E=1e-46 COG: YKR093w; COG3104 Dipeptide/tripeptide permease; E=2e-24 PFAM: PF00854; POT family; E=6.4e-42.
 
  
 0.407
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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