STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB9354Conserved hypothetical protein. (183 aa)    
Predicted Functional Partners:
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
  
 
 0.721
RB9352
Uncharacterized protein; PMID: 2585490 best DB hits: BLAST: embl:CAA35604.1; (X17591) HsdS polypeptide, part of CfrA family; E=0.17 pir:NDECAS; type I site-specific deoxyribonuclease (EC 3.1.21.3); E=0.17 swissprot:P19705; T1SE_ECOLI TYPE I RESTRICTION ENZYME ECOEI; E=0.17.
       0.572
RB9353
Probable modification methylase-putative transcriptional regulator; PMID: 7607524 best DB hits: BLAST: swissprot:P50196; MTE8_ECOLI MODIFICATION METHYLASE ECO47II; E=0.004 swissprot:P55393; Y4CK_RHISN PUTATIVE REPLICATION PROTEIN A; E=0.35.
       0.572
RB12303
Best DB hits: BLAST: pir:H69064; serinethreonine protein kinase related protein -; E=3e-04 gb:AAG20856.1; (AE005154) Vng6189h [Halobacterium sp. NRC-1]; E=0.007 gb:AAF16758.1; AC010155_11 (AC010155) F3M18.23 [Arabidopsis; E=0.014 COG: MTH1485; COG1520 Uncharacterized proteins of WD40-like repeat family; E=3e-05 PFAM: PF01011; PQQ enzyme repeat; E=0.0074.
  
     0.453
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.430
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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