STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cls-2Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. (491 aa)    
Predicted Functional Partners:
cls
Cardiolipin synthase; PMID: 1663113 PMID: 9370333 best DB hits: BLAST: pir:B82971; cardiolipin synthase PA5394 [imported] - Pseudomonas; E=3e-42 swissprot:P71040; CLS2_BACSU PROBABLE CARDIOLIPIN SYNTHETASE 2; E=4e-42 swissprot:P31048; CLS_PSEPU PROBABLE CARDIOLIPIN SYNTHETASE; E=5e-42 COG: PA5394; COG1502; E=2e-43 cls; COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiol; E=9e-32 BS_ywjE; COG1502; E=2e-31 PFAM: PF00614; Phospholipase D. Active site motif; E=1.2e-05.
  
  
 
0.925
RB9532
Hypothetical protein.
       0.773
uroD
Uroporphyrinogen III synthase, uroporhyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
     
 0.707
ykbA
Amino acid permease homolog ykbA; PMID: http://us.expasy.org/cgi-bin/niceprot.pl?Q9WVR6 best DB hits: BLAST: pir:B69855; amino acid permease homolog ykbA - Bacillus subtilis; E=4e-13 swissprot:Q9WVR6; LAT2_RAT LARGE NEUTRAL AMINO ACIDS TRANSPORTER; E=2e-11 embl:CAB69072.1; (Y19022) LAT2 protein [Mus musculus]; E=3e-11 COG: BS_ykbA; COG0531 Amino acid transporters; E=4e-14.
  
  
 0.669
tadB
Conserved hypothetical protein; PMID: 10880436 best DB hits: BLAST: gb:AAF40196.1; AF229646_8 (AF229646) TadB [Caulobacter crescentus]; E=9e-20 pir:D83108; hypothetical protein PA4301 [imported] - Pseudomonas; E=6e-11 embl:CAB92603.1; (AL356813) putative integral membrane protein; E=7e-06 COG: PA4301; COG2064 Predicted membrane protein; E=5e-12.
      
 0.610
tadB-2
Probable protein secretion system or pilus assembly related protein TadB; PMID: 11029439 best DB hits: BLAST: gb:AAF40196.1; AF229646_8 (AF229646) TadB [Caulobacter crescentus]; E=0.005 gb:AAD38173.2; AF152598_2 (AF152598) TadB [Actinobacillus; E=0.41.
      
 0.610
tadB-3
Secretion system protein TadB; PMID: 10880436 best DB hits: BLAST: gb:AAF40196.1; AF229646_8 (AF229646) TadB [Caulobacter crescentus]; E=2e-19 pir:D83108; hypothetical protein PA4301 [imported] - Pseudomonas; E=5e-12 embl:CAB92603.1; (AL356813) putative integral membrane protein; E=2e-09 COG: PA4301; COG2064 Predicted membrane protein; E=5e-13.
      
 0.610
tadC
Probable secretion system protein TadC; PMID: 10880436 best DB hits: BLAST: embl:CAB92604.1; (AL356813) putative integral membrane protein; E=6e-09 gb:AAK02931.1; (AE006123) TadC [Pasteurella multocida]; E=2e-08 pir:C83108; hypothetical protein PA4300 [imported] - Pseudomonas; E=3e-08 COG: PH0653; COG2064 Predicted membrane protein; E=3e-05.
      
 0.602
aslA-7
Arylsulfatase; PMID: 10336424 best DB hits: BLAST: swissprot:P25549; ASLA_ECOLI ARYLSULFATASE (ARYL-SULFATE; E=4e-62 gb:AAG58993.1; AE005611_3 (AE005611) arylsulfatase [Escherichia; E=6e-62 gb:AAC32036.1; (M90498) putative arylsulfatase [Escherichia coli]; E=1e-54 COG: aslA; COG3119 Arylsulfatase A and related enzymes; E=4e-63 PFAM: PF00884; Sulfatase; E=3.6e-42.
       0.568
ctpA
Carboxyl-terminal processing protease; PMID: 8034700 PMID: 8058761 best DB hits: BLAST: pir:F70144; carboxyl-terminal processing proteinase (ctp) homolog -; E=1e-42 pir:A71677; tail-specific proteinase precursor (ctp) RP228 -; E=2e-41 pir:B83005; probable carboxyl-terminal proteinase PA5134 [imported]; E=8e-40 COG: BB0359; COG0793 Periplasmic protease; E=1e-43 PFAM: PF00515; TPR Domain; E=0.18 PF00595; PDZ domain (Also known as DHR or GLG; E=4.7e-05; Belongs to the peptidase S41A family.
  
  
 0.547
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.