| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AFE_0017 | minC | AFE_0017 | AFE_0013 | DNA processing protein DprA, putative; Identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732. | Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | 0.577 |
| AFE_0017 | minD | AFE_0017 | AFE_0012 | DNA processing protein DprA, putative; Identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732. | Septum site-determining protein MinD; Identified by similarity to SP:P18197; match to protein family HMM PF01656; match to protein family HMM TIGR01968. | 0.585 |
| AFE_0017 | minE | AFE_0017 | AFE_0011 | DNA processing protein DprA, putative; Identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732. | Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | 0.585 |
| AFE_0017 | smg | AFE_0017 | AFE_0016 | DNA processing protein DprA, putative; Identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732. | Smg family protein; Belongs to the Smg family. | 0.799 |
| AFE_0017 | topA | AFE_0017 | AFE_0015 | DNA processing protein DprA, putative; Identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.892 |
| AFE_1091 | minE | AFE_1091 | AFE_0011 | Conjugation signal peptidase TraF, putative; Identified by similarity to SP:P26844; similarity to GB:AAL59670.1. | Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | 0.691 |
| AFE_1726 | minE | AFE_1726 | AFE_0011 | Conjugal transfer protein TraF, putative; Identified by similarity to SP:Q44350. | Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | 0.691 |
| AFE_2763 | lepB | AFE_2763 | AFE_1398 | Outer membrane lipoprotein LolB, putative; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | Signal peptidase I; Identified by similarity to SP:P26844; match to protein family HMM PF00717; match to protein family HMM TIGR02227; Belongs to the peptidase S26 family. | 0.524 |
| AFE_2763 | minE | AFE_2763 | AFE_0011 | Outer membrane lipoprotein LolB, putative; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | 0.807 |
| lepB | AFE_2763 | AFE_1398 | AFE_2763 | Signal peptidase I; Identified by similarity to SP:P26844; match to protein family HMM PF00717; match to protein family HMM TIGR02227; Belongs to the peptidase S26 family. | Outer membrane lipoprotein LolB, putative; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | 0.524 |
| lepB | minE | AFE_1398 | AFE_0011 | Signal peptidase I; Identified by similarity to SP:P26844; match to protein family HMM PF00717; match to protein family HMM TIGR02227; Belongs to the peptidase S26 family. | Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | 0.780 |
| lepB | phoU | AFE_1398 | AFE_1440 | Signal peptidase I; Identified by similarity to SP:P26844; match to protein family HMM PF00717; match to protein family HMM TIGR02227; Belongs to the peptidase S26 family. | Phosphate transport system protein PhoU; Plays a role in the regulation of phosphate uptake. | 0.401 |
| lepB | topA | AFE_1398 | AFE_0015 | Signal peptidase I; Identified by similarity to SP:P26844; match to protein family HMM PF00717; match to protein family HMM TIGR02227; Belongs to the peptidase S26 family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.511 |
| minC | AFE_0017 | AFE_0013 | AFE_0017 | Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | DNA processing protein DprA, putative; Identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732. | 0.577 |
| minC | minD | AFE_0013 | AFE_0012 | Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | Septum site-determining protein MinD; Identified by similarity to SP:P18197; match to protein family HMM PF01656; match to protein family HMM TIGR01968. | 0.999 |
| minC | minE | AFE_0013 | AFE_0011 | Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | 0.953 |
| minC | smg | AFE_0013 | AFE_0016 | Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | Smg family protein; Belongs to the Smg family. | 0.578 |
| minC | topA | AFE_0013 | AFE_0015 | Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.578 |
| minD | AFE_0017 | AFE_0012 | AFE_0017 | Septum site-determining protein MinD; Identified by similarity to SP:P18197; match to protein family HMM PF01656; match to protein family HMM TIGR01968. | DNA processing protein DprA, putative; Identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732. | 0.585 |
| minD | minC | AFE_0012 | AFE_0013 | Septum site-determining protein MinD; Identified by similarity to SP:P18197; match to protein family HMM PF01656; match to protein family HMM TIGR01968. | Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | 0.999 |
