Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_0022Hypothetical protein; Identified by glimmer; putative. (199 aa)    
Predicted Functional Partners:
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
       0.799
sun
Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
       0.799
def-2
Polypeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
       0.788
AFE_0602
Cation ABC transporter, periplasmic cation-binding protein, putative; Identified by match to protein family HMM PF01297.
      
 0.724
AFE_0603
Cation ABC transporter, ATP-binding protein, putative; Identified by match to protein family HMM PF00005.
      
 0.724
AFE_0604
Cation ABC transporter, permease protein, putative; Identified by match to protein family HMM PF00950.
      
 0.724
AFE_1788
Membrane-associated zinc metalloprotease, putative; Identified by similarity to GB:CAD85637.1; match to protein family HMM PF02163.
      
 0.724
AFE_1143
Hypothetical protein; Identified by glimmer; putative.
      
 0.716
ntrY
Nitrogen regulation protein NtrY, putative; Identified by similarity to SP:Q04850; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518.
       0.659
smg
Smg family protein; Belongs to the Smg family.
  
    0.620
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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