Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_0030Hypothetical protein; Identified by glimmer; putative. (393 aa)    
Predicted Functional Partners:
AFE_0969
Type IV pilin, putative; Identified by match to protein family HMM TIGR02532.
  
     0.745
AFE_0620
Hypothetical protein; Identified by glimmer; putative.
  
     0.701
AFE_1755
Conserved hypothetical protein; Identified by similarity to GB:AAN66820.1.
  
     0.693
pdhC
Pyruvate dehydrogenase complex, E2 and E3 components; Dihydrolipoamide acetyltransferase/dihydrolipoamide dehydrogenase; identified by similarity to PIR:C59237; match to protein family HMM PF00070; match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817; match to protein family HMM PF02852; match to protein family HMM PF07992.
  
    0.660
AFE_2677
3-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
  
     0.646
AFE_0458
Rare lipoprotein B, putative; Identified by similarity to SP:P10101.
  
     0.640
cscB
Carboxysome peptide B; Identified by similarity to GB:AAD30513.1; match to protein family HMM PF03319; match to protein family HMM TIGR02704.
  
     0.624
AFE_1824
Membrane protein, putative.
  
     0.620
AFE_2896
Identified by match to protein family HMM PF04932.
  
     0.613
AFE_2037
Outer membrane efflux protein; Identified by match to protein family HMM PF02321.
  
     0.599
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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