Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AFE_0040Drug resistance transporter, EmrB/QacA family; Identified by match to protein family HMM PF07690. (540 aa)    
Predicted Functional Partners:
AFE_0038
Drug resistance secretion protein, putative; Identified by match to protein family HMM PF00529.
 
   0.961
AFE_0039
RND efflux system, drug efflux transporter, outer membrane lipoprotein; Identified by match to protein family HMM PF02321; match to protein family HMM TIGR01845.
 
   0.870
AFE_0862
Drug resistance transporter, putative; Identified by match to protein family HMM PF00529.
 
   0.836
AFE_0257
Secretion protein, HlyD family; Identified by match to protein family HMM PF00529.
 
   0.828
AFE_0037
Transcriptional regulator, LysR family; Identified by match to protein family HMM PF00126; match to protein family HMM PF03466; Belongs to the LysR transcriptional regulatory family.
       0.592
AFE_0863
RND efflux system, drug efflux transporter, outer membrane lipoprotein; Identified by match to protein family HMM PF02321; match to protein family HMM TIGR01845.
  
   0.445
AFE_2690
Type I secretion outer membrane protein, putative; Identified by match to protein family HMM PF02321.
  
   0.441
AFE_0036
ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005.
       0.418
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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