Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AFE_0041C4-dicarboxylate transporter/malic acid transport protein; Identified by match to protein family HMM PF03595. (385 aa)    
Predicted Functional Partners:
AFE_3090
Membrane protein, putative; Identified by match to protein family HMM PF07690.
  
     0.670
AFE_0042
Tat (twin-arginine translocation) pathway signal sequence domain protein; Identified by match to protein family HMM TIGR01409.
       0.642
AFE_0043
Periplasmic solute-binding protein, putative; Identified by similarity to SP:P27366.
 
     0.628
AFE_1498
ABC transporter, periplasmic substrate-binding protein, putative; Identified by match to protein family HMM PF01547.
  
     0.595
AFE_2019
Conserved domain protein.
  
     0.536
doxD_2
Identified by match to protein family HMM PF07681.
 
     0.523
AFE_2018
Conserved hypothetical protein; Identified by similarity to PIR:C70988.
  
     0.502
AFE_2089
Hypothetical protein; Identified by glimmer; putative.
  
     0.442
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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