Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
doxD_2Identified by match to protein family HMM PF07681. (356 aa)    
Predicted Functional Partners:
tetH
Tetrathionate hydrolase; Catalyzes the hydrolysis of tetrathionate to generate elemental sulfur, thiosulfate and sulfate.
 
  
 0.982
doxD_1
Identified by match to protein family HMM PF07681.
  
  
0.902
AFE_0026
Sensor histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518.
  
   
 0.751
AFE_0042
Tat (twin-arginine translocation) pathway signal sequence domain protein; Identified by match to protein family HMM TIGR01409.
     
 0.722
AFE_0969
Type IV pilin, putative; Identified by match to protein family HMM TIGR02532.
  
     0.711
AFE_2677
3-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
  
     0.677
AFE_3099
Hypothetical protein; Identified by glimmer; putative.
  
     0.671
AFE_3115
Conserved hypothetical protein; Identified by similarity to SP:O67860.
  
     0.655
AFE_0458
Rare lipoprotein B, putative; Identified by similarity to SP:P10101.
  
     0.645
AFE_0967
Type IV pilin biogenesis protein, putative; Identified by similarity to GB:AAQ58159.1.
  
     0.642
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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