Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_0049Periplasmic solute-binding protein, putative; Identified by similarity to SP:P27366. (337 aa)    
Predicted Functional Partners:
AFE_0050
Tat (twin-arginine translocation) pathway signal sequence domain protein; Identified by match to protein family HMM TIGR01409.
       0.714
doxD_1
Identified by match to protein family HMM PF07681.
       0.613
AFE_2190
ABC transporter, permease protein; Identified by match to protein family HMM PF00528.
 
 
 0.532
AFE_0051
Hypothetical protein; Identified by glimmer; putative.
       0.531
AFE_0047
Conserved hypothetical protein; Identified by similarity to GB:BAC46291.1; match to protein family HMM PF00578; match to protein family HMM PF08534.
       0.435
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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